The persecution of Christians can be traced from the first century of the Christian era to the present day. Christian missionaries and converts to Christianity have both been targeted for persecution, sometimes to the point of being martyred for their faith, ever since the emergence of Christianity.
Early Christians were persecuted at the hands of both Jews, from whose religion Christianity arose, and the Romans who controlled many of the early centers of Christianity in the Roman Empire. Since the emergence of Christian states in Late Antiquity, Christians have also been persecuted by other Christians due to differences in doctrine which have been declared heretical. Early in the fourth century, the empire's official persecutions were ended by the Edict of Serdica in 311 and the practice of Christianity legalized by the Edict of Milan in 312. By the year 380, Christians had begun to persecute each other. The schisms of late antiquity and the Middle Ages – including the Rome–Constantinople schisms and the many Christological controversies – together with the later Protestant Reformation provoked severe conflicts between Christian denominations. During these conflicts, members of the various denominations frequently persecuted each other and engaged in sectarian violence.
