Giannitsa (Greek: Γιαννιτσά [ʝaniˈt͡sa], in English also Yannitsa, Yenitsa) is the largest city in the regional unit of Pella and the capital of the Pella municipality, in the region of Central Macedonia in northern Greece.
The municipal unit Giannitsa has an area of 208.105 km. Its population is 32,410 people (2021 census). It includes a few outlying villages (Mesiano, Melissi, Pentaplatanos, Archontiko, Ampelies and Damiano). The municipality Pella as a whole includes many villages and has 57,039 inhabitants. The city is located in the center of Macedonia between Mount Paiko and the plain of Giannitsa, and is the economic, commercial and industrial center of the Pella regional unit. European route E86 (Greek National Road 2) runs along the south of the city.