Naso Tjër Di (meaning “I am from the grandmother's river") is a landlocked indigenous region of Panama, located in the extreme northwest of the country, on the banks of the Teribe River and adjacent to the border between Costa Rica and Panama. The region is inhabited mainly by the Naso ethnic group, which is made up of about 5000 people.
It was created on December 4, 2020 from parts of Changuinola, and has an area of 1,606.16 square kilometres (620.14 sq mi), of which 1468.63 km (91% of the territory) are protected areas of the La Amistad International Park and the Palo Seco Forest Reserve.