Othón P. Blanco is one of the eleven subdivisions (municipios) of the Mexican state of Quintana Roo. It had a 2020 census population of 233,648 people. Its municipal seat is the city of Chetumal, which also serves as the state capital. The municipality is named after Othón P. Blanco Núñez de Cáceres.
The municipal government is headed by the municipal president of Othón P. Blanco (mayor of Othón P. Blanco, aka mayor of Chetumal).