Orlu (Igbo: Ọ̀lụ́) is the second-largest city in Imo State, South East, Nigeria, with a population of 420,600. It has a long history as the headquarters for the Organisation of African Unity (OAU) and humanitarian relief agencies during the Nigeria-Biafra Civil War. The city houses the Nigerian headquarters of the British Cheshire Home. It is the second most developed city in Imo state after Owerri.