Ocean City, Maryland in the context of "U.S. Route 50 in Virginia"

The Gov. William Preston Lane Jr. Memorial Bridge (informally called the Chesapeake Bay Bridge and, locally, the Bay Bridge) is a major dual-span bridge in the U.S. state of Maryland. Spanning the Chesapeake Bay, it connects the state's rural Eastern Shore region with its urban and suburban Western Shore, running between Stevensville and Sandy Point State Park near the capital city of Annapolis. The original span, opened in 1952 and with a length of 4 miles (6.4 km), was the world's longest continuous over-water steel structure. The parallel span was added in 1973. The bridge is named for William Preston Lane Jr., who, as the 52nd Governor of Maryland, launched its construction in the late 1940s after decades of political indecision and public controversy.

The bridge is part of U.S. Route 50 (US 50) and US 301, and serves as a vital link in both routes. As part of cross-country US 50, it connects the Baltimore–Washington Metropolitan Area with Ocean City, Maryland, Rehoboth Beach, Delaware, and other coastal tourist destinations. As part of US 301, it serves as part of an alternative route for Interstate 95 travelers, between northern Delaware and the Washington, D.C., area. The bridge is busy and often congested with traffic, particularly during peak hours and summer months.

U.S. Route 50 (US 50) (also called Ocean Gateway) is a major east–west route of the U.S. Highway system, stretching just over 3,000 miles (4,800 km) from West Sacramento, California, east to Ocean City, Maryland, on the Atlantic Ocean. In the U.S. state of Maryland, US 50 exists in two sections. The longer of these serves as a major route connecting Washington, D.C., with Ocean City, which is the eastern terminus of the highway. The other section passes through the southern end of Garrett County for less than 10 miles (16 km) as part of the Northwestern Turnpike, entering West Virginia at both ends. One notable section of US 50 is the dual-span Chesapeake Bay Bridge across the Chesapeake Bay, which links the Baltimore–Washington metropolitan area with the Eastern Shore region, allowing motorists to reach Ocean City and the Delaware Beaches.

US 50 has received numerous upgrades during its existence in Maryland, including the construction of the John Hanson Highway, a portion of which is also the unsigned Interstate 595 (I-595), its extension onto the Eastern Shore and replacement of US 213 due to the construction of the Chesapeake Bay Bridge, and the full conversion of the eastern segment of the route into a four-lane divided highway. Many of the older alignments of US 50 are still part of the Maryland and US highway systems, such as US 50 Business (US 50 Bus.) in Salisbury. US 50 continues to be upgraded on the Eastern Shore.

U.S. Route 50 (US 50) is a major east–west route of the U.S. Highway System, stretching just over 3,000 miles (4,800 km) from Ocean City, Maryland, on the Atlantic Ocean, to West Sacramento, California, nearly to the Pacific Ocean. In Washington, D.C., US 50 passes between Arlington County, Virginia, and Prince George's County, Maryland, predominantly along surface streets, including a part of Constitution Avenue along the National Mall.

U.S. Route 50 or U.S. Highway 50 (US 50) is a major east–west route of the U.S. Highway system, stretching 3,019 miles (4,859 km) from Interstate 80 (I-80) in West Sacramento, California, to Maryland Route 528 (MD 528) in Ocean City, Maryland, on the Atlantic Ocean. Until 1972, when it was replaced by Interstate Highways west of the Sacramento area, it extended (by way of Stockton, the Altamont Pass, and the Bay Bridge) to San Francisco, near the Pacific Ocean. The Interstates were constructed later and are mostly separate from this route. It generally serves a corridor south of I-70 and I-80 and north of I-64 and I-40.

The route runs through mostly rural desert and mountains in the western United States, with the section through Nevada known as "The Loneliest Road in America". In the Midwest, US 50 heads through mostly rural areas of farms as well as a few large cities including Kansas City, Missouri; St. Louis, Missouri; and Cincinnati, Ohio.