Nucleic acid test in the context of "Rapid antigen test"

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👉 Nucleic acid test in the context of Rapid antigen test

A rapid antigen test (RAT), sometimes called a rapid antigen detection test (RADT), antigen rapid test (ART), or loosely just a rapid test, is a rapid diagnostic test suitable for point-of-care testing that directly detects the presence or absence of an antigen. RATs are a type of lateral flow test detecting antigens, rather than antibodies (antibody tests) or nucleic acid (nucleic acid tests). Rapid tests generally give a result in 5 to 30 minutes, require minimal training or infrastructure, and have significant cost advantages. Rapid antigen tests for the detection of SARS-CoV-2, the virus that causes COVID-19, have been commonly used during the COVID-19 pandemic.

For many years, an early and major class of RATs—the rapid strep tests for streptococci—were so often the referent when RATs or RADTs were mentioned that the two latter terms were often loosely treated as synonymous with those. Since the COVID-19 pandemic, awareness of RATs is no longer limited to health professionals and COVID-19 has become the expected referent, so more precise usage is required in other circumstances.

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Nucleic acid test in the context of Cervical screening

Cervical cancer screening is a medical screening test designed to identify risk of cervical cancer. Cervical screening may involve looking for viral DNA, and/or identifying abnormal, potentially precancerous cells within the cervix as well as cells that have progressed to early stages of cervical cancer. One goal of cervical screening is to allow for intervention and treatment so abnormal lesions can be removed before progression to cancer. An additional goal is to decrease mortality from cervical cancer by identifying cancerous lesions in their early stages and providing treatment before progression to more invasive disease.

Currently available screening tests fall into three categories: molecular, cytologic, and visual inspection. Molecular screening tests include nucleic acid amplification tests (NAAT), which identify high-risk human papillomavirus (HPV) strains. Cytologic tests include conventional Pap smear and liquid-based cytology. Visual Inspection tests involve application of a solution to enhance identification of abnormal areas and can utilize the naked eye or a colposcope/magnifying camera.

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