The skull, or cranium, is typically a bony enclosure around the brain of a vertebrate. In some fish and amphibians, the skull is of cartilage. The skull is at the head end of the vertebrate.
In the human, the skull comprises two prominent parts: the neurocranium and the facial skeleton, which evolved from the first pharyngeal arch. The skull forms the frontmost portion of the axial skeleton and is a product of cephalization and vesicular enlargement of the brain, with several special senses structures such as the eyes, ears, nose, tongue and, in fish, specialized tactile organs such as barbels near the mouth.