The East Siberian Lowland (Russian: Восточно-Сибирская низменность, romanized: Vostochno-Sibirskaya nizmennost), also known as Yana-Kolyma Lowland (Russian: Яно-Колымская низменность, romanized: Yano-Kolymskaya nizmennost), is a vast plain in North-eastern Siberia, Russia. The territory of the lowland is one of the Great Russian Regions. Administratively, it is a part of the Sakha Republic (Yakutia).
Owing to the harshness of the climate the East Siberian Lowland is largely unpopulated. Inhabited centers are small and widely scattered. Andryushkino, Argakhtakh, Chokurdakh, Nizhneyansk, Olenegorsk, Russkoye Ustye, Srednekolymsk, and Zyryanka are among the few towns in the area.