Nicander of Colophon (Ancient Greek: Νίκανδρος ὁ Κολοφώνιος, romanized: Níkandros ho Kolophṓnios; fl. 2nd century BC) was a Greek poet, physician, and grammarian.
The scattered biographical details in the ancient sources are so contradictory that it was sometimes assumed that there were two Hellenistic authors with the same name. He may have been born at Claros (Ahmetbeyli in modern Turkey), near Colophon, where his family is said to have held the hereditary priesthood of Apollo. The chronological indications range from the middle of the 3rd century BC until the late 2nd century BC.