The National Institute for Occupational Safety and Health (NIOSH, /ˈnaɪɒʃ/) is the United States federal agency responsible for conducting research and making recommendations for the prevention of work-related injury, illness, disability, and death. Its functions include gathering information, conducting scientific research both in the laboratory and in the field, and translating the knowledge gained into products and services. Among NIOSH's programs are determination of recommended exposure limits for toxic chemicals and other hazards, field research such as the Health Hazard Evaluation Program, epidemiology and health surveillance programs such as the National Firefighter Registry for Cancer, regulatory approval of respirators according to the NIOSH air filtration rating system, and compensation and support programs such as the World Trade Center Health Program.
The Occupational Safety and Health Act, signed by President Richard M. Nixon on December 29, 1970, created NIOSH out of the preexisting Division of Industrial Hygiene founded in 1914. NIOSH is part of the Centers for Disease Control and Prevention within the Department of Health and Human Services (HHS). Despite the similarities in names, it is not part of the National Institutes of Health or OSHA, which have distinct and separate responsibilities.