Nammu in the context of Incantation

Anu (Akkadian: 𒀭𒀀𒉡 ANU, from 𒀭 an "Sky", "Heaven") or Anum, originally An (Sumerian: 𒀭 An), was the divine personification of the sky, king of the gods, and ancestor of many of the deities in ancient Mesopotamian religion. He was regarded as a source of both divine and human kingship, and opens the enumerations of deities in many Mesopotamian texts. At the same time, his role was largely passive, and he was not commonly worshipped. It is sometimes proposed that the Eanna temple located in Uruk originally belonged to him, rather than Inanna. While he is well attested as one of its divine inhabitants, there is no evidence that the main deity of the temple ever changed; Inanna was already associated with it in the earliest sources. After it declined, a new theological system developed in the same city under Seleucid rule, resulting in Anu being redefined as an active deity. As a result he was actively worshipped by inhabitants of the city in the final centuries of the history of ancient Mesopotamia.

Multiple traditions regarding the identity of Anu's spouse existed, though three of them—Ki, Urash, and Antu—were at various points in time equated with each other, and all three represented earth, similar to how he represented heaven. In a fourth tradition, more sparsely attested, his wife was the goddess Nammu instead. In addition to listing his spouses and children, god lists also often enumerated his various ancestors, such as Anshar or Alala. A variant of one such family tree formed the basis of the Enūma Eliš.

Uraš (Sumerian: 𒀭𒅁, romanized: Uraš), or Urash, was a Mesopotamian goddess regarded as the personification of the earth. She should not be confused with a male deity sharing the same name, who had agricultural character and was worshiped in Dilbat. She is well attested in association with Anu, most commonly as his spouse, though traditions according to which she was one of his ancestors or even his alternate name are also known. She could be equated with other goddesses who could be considered his wives, namely Ki and Antu, though they were not always regarded as identical. Numerous deities were regarded as children of Urash and Anu, for example Ninisina and Ishkur. However, in some cases multiple genealogies existed, for example Enki was usually regarded as the son of Nammu and Geshtinanna of Duttur, even though texts describing them as children of Urash exist. Not much evidence for the worship of Urash is available, though offerings to her are mentioned in documents from the Ur III period and it is possible she had a temple in Nippur.

Nanshe (Sumerian: 𒀭𒀏 NANŠE (AB×ḪA)) was a Mesopotamian goddess in various contexts associated with the sea, marshlands, the animals inhabiting these biomes, namely bird and fish, as well as divination, dream interpretation, justice, social welfare, and certain administrative tasks. She was regarded as a daughter of Enki and sister of Ningirsu, while her husband was Nindara, who is otherwise little known. Other deities who belonged to her circle included her daughter Nin-MAR.KI, as well as Hendursaga, Dumuzi-abzu and Shul-utula. In Ur she was incorporated into the circle of Ningal, while in incantations she appears alongside Ningirima or Nammu.

The oldest attestations of the worship of Nanshe come from the Uruk period. Her cult center was Tell Zurghul, known in antiquity as Nina. Another place associated with her, Sirara, was likely a sacred district in this city. She was also worshiped elsewhere in the state of Lagash. Sanctuaries dedicated to her existed in its eponymous capital, as well as in Girsu, Gu'abba and other settlements. She is also attested in a number of other cities in other parts of Mesopotamia, including Adab, Nippur, Umma, Ur and Uruk, but her importance in their local pantheons was comparatively smaller. Her cult declined after the Ur III period. She was later adopted as a dynastic tutelary deity by the kings of the Sealand, and also came to be worshiped in the Esagil temple complex in Babylon. She was still venerated in the sixth century BCE.