Many gases have toxic properties, which are often assessed using the LC50 (median lethal concentration) measure. In the United States, many of these gases have been assigned an NFPA 704 health rating of 4 (may be fatal) or 3 (may cause serious or permanent injury), and/or exposure limits (TLV, TWA/PEL, STEL, or REL) determined by the ACGIH professional association. Some, but by no means all, toxic gases are detectable by odor, which can serve as a warning. Among the best known toxic gases are carbon monoxide, chlorine, nitrogen dioxide and phosgene.
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NFPA 704 in the context of Hydrogen safety
Hydrogen safety covers the safe production, handling and use of hydrogen, particularly hydrogen gas fuel and liquid hydrogen. Hydrogen possesses the NFPA 704's highest rating of four on the flammability scale because it is flammable when mixed even in small amounts with ordinary air. Ignition can occur at a volumetric ratio of hydrogen to air as low as 4% due to the oxygen in the air and the simplicity and chemical properties of the reaction. However, hydrogen has no rating for innate hazard for reactivity or toxicity. The storage and use of hydrogen poses unique challenges due to its ease of leaking as a gaseous fuel, low-energy ignition, wide range of combustible fuel-air mixtures, buoyancy, and its ability to embrittle metals that must be accounted for to ensure safe operation.
Liquid hydrogen poses additional challenges due to its increased density and the extremely low temperatures needed to keep it in liquid form. Moreover, its demand and use in industry—as rocket fuel, alternative energy storage source, coolant for electric generators in power stations, a feedstock in industrial and chemical processes including production of ammonia and methanol, etc.—has continued to increase, which has led to the increased importance of considerations of safety protocols in producing, storing, transferring, and using hydrogen.
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