Muscle contraction in the context of Swallowing

Adenosine triphosphate (ATP) is a nucleoside triphosphate that provides energy of approximate 30.5kJ/mol to drive and support many processes in living cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis. Found in all known forms of life, it is often referred to as the "molecular unit of currency" for intracellular energy transfer.

When consumed in a metabolic process, ATP converts either to adenosine diphosphate (ADP) or to adenosine monophosphate (AMP). Other processes regenerate ATP. It is also a precursor to DNA and RNA, and is used as a coenzyme. An average adult human processes around 50 kilograms (about 100 moles) daily.

Adenine (symbol A, or Ade) is a purine nucleotide base that is found in DNA, RNA, and ATP. Usually a white crystalline subtance. The shape of adenine is complementary and pairs to either thymine in DNA or uracil in RNA. In cells adenine, as an independent molecule, is rare. It is almost always covalently bound to become a part of a larger biomolecule.

Adenine has a central role in cellular respiration. It is part of adenosine triphosphate which provides the energy that drives and supports most activities in living cells, such as protein synthesis, chemical synthesis, muscle contraction, and nerve impulse propagation. In respiration it also participates as part of the cofactors nicotinamide adenine dinucleotide, flavin adenine dinucleotide, and Coenzyme A.

Soft-bodied organisms are organisms that lack rigid physical skeletons or frame, roughly corresponds to the group Vermes as proposed by Carl von Linné. The term typically refers to non-panarthropod invertebrates from the kingdom Animalia, although many non-vascular plants (mosses and algae), fungi (such as jelly fungus), lichens and slime molds can also be seen as soft-bodied organisms by definition.

All animals have a muscular system of some sort but, since myocytes are tensile actuator units that can only contract and pull but never push, some animals evolved rigid body parts upon which the muscles can attach and act as levers/cantilevers to redirect force and produce locomotive propulsion. These rigid parts also serve as structural elements to resist gravity and ambient pressure, as well as sometimes provide protective surfaces shielding internal structures from trauma and exposure to external thermal, chemical and pathogenic insults. Such physical structures are the commonly referred "skeletons", which may be internal (as in vertebrates, echinoderms and sponges) or external (as in arthropods and non-coleoid molluscs). However, many soft-bodied animals do still have a functional skeleton maintained by body fluid hydrostatics known as a hydroskeleton, such as that of earthworms, jellyfish, tapeworms, squids and an enormous variety of invertebrates from almost every phyla of the animal kingdom; and many have hardened teeth that allow them to chew, bite and burrow despite the rest of body being soft.

Muscle is a soft tissue, one of the four basic types of animal tissue. There are three types of muscle tissue in vertebrates: skeletal muscle, cardiac muscle, and smooth muscle. Muscle tissue gives skeletal muscles the ability to contract. Muscle tissue contains special contractile proteins called actin and myosin which interact to cause movement. Among many other muscle proteins present are two regulatory proteins, troponin and tropomyosin. Muscle is formed during embryonic development, in a process known as myogenesis.

Skeletal muscle tissue is striated, consisting of elongated, multinucleate muscle cells called muscle fibers, and is responsible for movements of the body. Other tissues in skeletal muscle include tendons and perimysium. Smooth and cardiac muscle contract involuntarily, without conscious intervention. These muscle types may be activated both through the interaction of the central nervous system as well as by innervation from peripheral plexus or endocrine (hormonal) activation. Skeletal muscle only contracts voluntarily, under the influence of the central nervous system. Reflexes are a form of non-conscious activation of skeletal muscles, but nonetheless arise through activation of the central nervous system, albeit not engaging cortical structures until after the contraction has occurred.

A tendon or sinew is a tough band of dense fibrous connective tissue that connects muscle to bone. It sends the mechanical forces of muscle contraction to the skeletal system, while withstanding tension.

Tendons, like ligaments, are made of collagen. The difference is that ligaments connect bone to bone, while tendons connect muscle to bone. There are about 4,000 tendons in the adult human body.

A cramp is a sudden, involuntary, painful contraction of one or more skeletal muscles, or an overshortening of such associated with electrical activity. While generally temporary and non-damaging, they can cause significant pain and a paralysis-like immobility of the affected muscle. A cramp usually goes away on its own over several seconds or (sometimes) minutes. Cramps are common and tend to occur at rest, usually at night (nocturnal leg cramps). They are also often associated with pregnancy, physical exercise or overexertion, and age (common in older adults); in such cases, cramps are called idiopathic because there is no underlying pathology. In addition to those benign conditions, cramps are also associated with many pathological conditions.

Cramp definition is narrower than the definition of muscle spasm: spasms include any involuntary abnormal muscle contractions, while cramps are sustained and painful. True cramps can be distinguished from other cramp-like conditions. Cramps are different from muscle contracture, which is also painful and involuntary, but which is electrically silent. The main distinguishing features of cramps from dystonia are suddenness with acute onset of pain, involvement of only one muscle, and spontaneous resolution of cramps or their resolution after stretching the affected muscle. Restless leg syndrome is not considered the same as muscle cramps and should not be confused with rest cramps. Cramps are sometimes also called a "Charley horse", which is the term used by the lay people.

Flaccid paralysis is a neurological condition characterized by weakness or paralysis and reduced muscle tone without other obvious cause (e.g., trauma). This abnormal condition may be caused by disease or by trauma affecting the nerves associated with the involved muscles. For example, if the somatic nerves to a skeletal muscle are severed, then the muscle will exhibit flaccid paralysis. When muscles enter this state, they become limp and cannot contract. This condition can become fatal if it affects the respiratory muscles, posing the threat of suffocation. It also occurs in the spinal shock stage in complete transection of the spinal cord occurring in injuries such as gunshot wounds.

Orgasm (from Greek ὀργασμός, orgasmos; "excitement, swelling"), sexual climax, or simply climax, is the sudden release of accumulated sexual excitement during the sexual response cycle, characterized by intense sexual pleasure resulting in rhythmic, involuntary muscular contractions in the pelvic region. Orgasms are controlled by the involuntary or autonomic nervous system and are experienced by both males and females; the body's response includes muscular spasms (in multiple areas), a general euphoric sensation, and, frequently, body movements and vocalizations. The period after orgasm (known as the resolution phase) is typically a relaxing experience due to the release of the neurohormones oxytocin and prolactin, as well as endorphins (or "endogenous morphine").

Human orgasms usually result from physical sexual stimulation of the penis in males (typically accompanied by ejaculation) and of the clitoris (and vagina) in females. Sexual stimulation can be by masturbation or with a sexual partner (penetrative sex, non-penetrative sex, or other sexual activity). Physical stimulation is not a requisite, as it is possible to reach orgasm through psychological means. Getting to orgasm may be difficult without a suitable psychological state. During sleep, a sex dream can trigger an orgasm and the release of sexual fluids (nocturnal emission).

A deformation can occur because of external loads, intrinsic activity (e.g. muscle contraction), body forces (such as gravity or electromagnetic forces), or changes in temperature, moisture content, or chemical reactions, etc.

A motor neuron (or motoneuron), also known as efferent neuron is a neuron that allows for both voluntary and involuntary movements of the body through muscles and glands. Its cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands. There are two types of motor neuron – upper motor neurons and lower motor neurons. Axons from upper motor neurons synapse onto interneurons in the spinal cord and occasionally directly onto lower motor neurons. The axons from the lower motor neurons are efferent nerve fibers that carry signals from the spinal cord to the effectors. Types of lower motor neurons are alpha motor neurons, beta motor neurons, and gamma motor neurons.

A single motor neuron may innervate many muscle fibres and a muscle fibre can undergo many action potentials in the time taken for a single muscle twitch. Innervation takes place at a neuromuscular junction and twitches can become superimposed as a result of summation or a tetanic contraction. Individual twitches can become indistinguishable, and tension rises smoothly eventually reaching a plateau.

Ejaculation is the discharge of semen (the ejaculate; normally containing sperm) from the penis through the urethra. It is the final stage and natural objective of male sexual stimulation, and an essential component of natural conception. After forming an erection, many men emit pre-ejaculatory fluid during stimulation prior to ejaculating. Ejaculation involves involuntary contractions of the pelvic floor and is normally linked with orgasm. It is a normal part of male human sexual development.

Ejaculation can occur spontaneously during sleep (a nocturnal emission or "wet dream") or in rare cases because of prostatic disease. Anejaculation is the condition of being unable to ejaculate. Dysejaculation is an ejaculation that is painful or uncomfortable. Retrograde ejaculation is the backward flow of semen from the urethra into the bladder. Premature ejaculation happens shortly after initiating sexual activity, and hinders prolonged sexual intercourse. A vasectomy alters the composition of the ejaculate as a form of birth control.

The somatic nervous system (SNS), also known as voluntary nervous system, is a part of the peripheral nervous system (PNS) that links brain and spinal cord to skeletal muscles under conscious control, as well as to sensory receptors in the skin. The other part complementary to the somatic nervous system is the autonomic nervous system (ANS).

The somatic nervous system consists of nerves carrying afferent nerve fibers, which relay sensation from the body to the central nervous system (CNS), and nerves carrying efferent nerve fibers, which relay motor commands from the CNS to stimulate muscle contraction. Specialized nerve fiber ends called sensory receptors are responsible for detecting information both inside and outside the body.

Smooth muscle is one of the three major types of vertebrate muscle tissue, the others being skeletal and cardiac muscle. It can also be found in invertebrates and is controlled by the autonomic nervous system. It is non-striated, so-called because it has no sarcomeres and therefore no striations (bands or stripes). It can be divided into two subgroups, single-unit and multi-unit smooth muscle. Within single-unit muscle, the whole bundle or sheet of smooth muscle cells contracts as a syncytium.

Smooth muscle is found in the walls of hollow organs, including the stomach, intestines, bladder and uterus. In the walls of blood vessels, and lymph vessels, (excluding blood and lymph capillaries) it is known as vascular smooth muscle. There is smooth muscle in the tracts of the respiratory, urinary, and reproductive systems. In the eyes, the ciliary muscles, iris dilator muscle, and iris sphincter muscle are types of smooth muscles. The iris dilator and sphincter muscles are contained in the iris and contract in order to dilate or constrict the pupils. The ciliary muscles change the shape of the lens to focus on objects in accommodation. In the skin, smooth muscle cells such as those of the arrector pili cause hair to stand erect in response to cold temperature and fear.

A spasm is a sudden involuntary contraction of a muscle, a group of muscles, or a hollow organ, such as the bladder.

A spasmodic muscle contraction may be caused by many medical conditions, including dystonia. Most commonly, it is a muscle cramp which is accompanied by a sudden burst of pain. A muscle cramp is usually harmless and ceases after a few minutes. It is typically caused by ion imbalance or muscle fatigue.

A tremor is an involuntary, somewhat rhythmic muscle contraction and relaxation involving oscillations or twitching movements of one or more body parts. It is the most common of all involuntary movements and can affect the hands, arms, eyes, face, head, vocal folds, trunk, and legs. Most tremors occur in the hands. In some people, a tremor is a symptom of another neurological disorder.

Swallowing, also called deglutition or inglutition in scientific and medical contexts, is a physical process of an animal's digestive tract (e.g. that of a human body) that allows for an ingested substance (typically food) to pass from the mouth to the pharynx and then into the esophagus. In colloquial English, the term "swallowing" is also used to describe the action of gulping, i.e. taking in a large mouthful of food without any biting.

Swallowing is performed by an initial push from back part of the tongue (with the tongue tip contacting the hard palate for mechanical anchorage) and subsequent coordinated contractions of the pharyngeal muscles. The portion of food, drink and/or other material (e.g. mucus, secretions and medications) that moves into the gullet in one swallow is called a bolus, which is then propelled through to the stomach for further digestion by autonomic peristalsis of the esophagus.