Morphogenesis in the context of "Patterns in nature"

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⭐ Core Definition: Morphogenesis

Morphogenesis (from the Greek morphê shape and genesis creation, literally "the generation of form") is the biological process that causes a cell, tissue or organism to develop its shape. It is one of three fundamental aspects of developmental biology along with the control of tissue growth and patterning of cellular differentiation.

The process controls the organized spatial distribution of cells during the embryonic development of an organism. Morphogenesis can take place also in a mature organism, such as in the normal maintenance of tissue by stem cells or in regeneration of tissues after damage. Cancer is an example of highly abnormal and pathological tissue morphogenesis. Morphogenesis also describes the development of unicellular life forms that do not have an embryonic stage in their life cycle. Morphogenesis is essential for the evolution of new forms.

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👉 Morphogenesis in the context of Patterns in nature

Patterns in nature are visible regularities of form found in the natural world. These patterns recur in different contexts and can sometimes be modelled mathematically. Natural patterns include symmetries, trees, spirals, meanders, waves, foams, tessellations, cracks and stripes. Early Greek philosophers studied pattern, with Plato, Pythagoras and Empedocles attempting to explain order in nature. The modern understanding of visible patterns developed gradually over time.

In the 19th century, the Belgian physicist Joseph Plateau examined soap films, leading him to formulate the concept of a minimal surface. The German biologist and artist Ernst Haeckel painted hundreds of marine organisms to emphasise their symmetry. Scottish biologist D'Arcy Thompson pioneered the study of growth patterns in both plants and animals, showing that simple equations could explain spiral growth. In the 20th century, the British mathematician Alan Turing predicted mechanisms of morphogenesis which give rise to patterns of spots and stripes. The Hungarian biologist Aristid Lindenmayer and the French American mathematician Benoît Mandelbrot showed how the mathematics of fractals could create plant growth patterns.

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Morphogenesis in the context of Regeneration (biology)

Regeneration in biology is the process of renewal, restoration, and tissue growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. Every species is capable of regeneration, from bacteria to humans. Regeneration can either be complete where the new tissue is the same as the lost tissue, or incomplete after which the necrotic tissue becomes fibrotic.

At its most elementary level, regeneration is mediated by the molecular processes of gene regulation and involves the cellular processes of cell proliferation, morphogenesis and cell differentiation. Regeneration in biology, however, mainly refers to the morphogenic processes that characterize the phenotypic plasticity of traits allowing multi-cellular organisms to repair and maintain the integrity of their physiological and morphological states. Above the genetic level, regeneration is fundamentally regulated by asexual cellular processes. Regeneration is different from reproduction. For example, hydra perform regeneration but reproduce by the method of budding.

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Morphogenesis in the context of Élan vital

Élan vital (French pronunciation: [elɑ̃ vital]) is a term coined by French philosopher Henri Bergson in his 1907 book Creative Evolution, in which he addresses the question of self-organisation and spontaneous morphogenesis of things in an increasingly complex manner. Élan vital was translated in the English edition as "vital impetus", but is usually translated by his detractors as "vital force". It is a hypothetical explanation for evolution and development of organisms, which Bergson linked closely with consciousness – the intuitive perception of experience and the flow of inner time.

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Morphogenesis in the context of Hindbrain

The hindbrain, rhombencephalon (shaped like a rhombus) is a developmental categorization of portions of the central nervous system in vertebrates. It includes the medulla, pons, and cerebellum. Together they support vital bodily processes.

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Morphogenesis in the context of D'Arcy Thompson

Sir D'Arcy Wentworth Thompson CB FRS FRSE (2 May 1860 – 21 June 1948) was a Scottish biologist, mathematician and classics scholar. He was a pioneer of mathematical and theoretical biology, travelled on expeditions to the Bering Strait and held the position of Professor of Natural History at University College, Dundee for 32 years, then at St Andrews for 31 years. He was elected a Fellow of the Royal Society, was knighted, and received the Darwin Medal and the Daniel Giraud Elliot Medal.

Thompson is remembered as the author of the 1917 book On Growth and Form, which led the way for the scientific explanation of morphogenesis, the process by which patterns and body structures are formed in plants and animals.

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Morphogenesis in the context of Gene regulatory network

A gene (or genetic) regulatory network (GRN) is a collection of molecular regulators that interact with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins which, in turn, determine the function of the cell. GRN also play a central role in morphogenesis, the creation of body structures, which in turn is central to evolutionary developmental biology (evo-devo).

The regulator can be DNA, RNA, protein or any combination of two or more of these three that form a complex, such as a specific sequence of DNA and a transcription factor to activate that sequence. The interaction can be direct or indirect (through transcribed RNA or translated protein). In general, each mRNA molecule goes on to make a specific protein (or set of proteins). In some cases this protein will be structural, and will accumulate at the cell membrane or within the cell to give it particular structural properties. In other cases the protein will be an enzyme, i.e., a micro-machine that catalyses a certain reaction, such as the breakdown of a food source or toxin. Some proteins though serve only to activate other genes, and these are the transcription factors that are the main players in regulatory networks or cascades. By binding to the promoter region at the start of other genes they turn them on, initiating the production of another protein, and so on. Some transcription factors are inhibitory.

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Morphogenesis in the context of Lactiferous duct

Lactiferous ducts are ducts that converge and form a branched system connecting the nipple to the lobules of the mammary gland. When lactogenesis occurs, under the influence of hormones, the milk is moved to the nipple by the action of smooth muscle contractions along the ductal system to the tip of the nipple. They are also referred to as galactophores, galactophorous ducts, mammary ducts, mamillary ducts or milk ducts.

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Morphogenesis in the context of Andy Lomas

Andy Lomas (born 1967 in Welwyn Garden City, England) is a British artist with a mathematical background, formerly a television and film CG supervisor and more recently a contemporary digital artist, with a special interest in morphogenesis using mathematical morphology.

Lomas previously worked on visual effects using computer graphics (CGI) for television and films such as The Matrix Reloaded (2003), The Matrix Revolutions (2003) and Avatar (2009). before becoming a digital artist. In 2006 he appeared in The Tech of 'Over the Hedge', a short documentary. With his collaborators, in 1999 Lomas won the 51st Primetime Emmy Awards Outstanding Special Visual Effects for a Miniseries or a Movie for the 1999 film Alice in Wonderland.

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