Mineralized tissues in the context of "Hard tissue"

A bone is a rigid organ that constitutes part of the skeleton in most vertebrate animals. Bones protect the organs of the body, produce red and white blood cells, store minerals, help regulate acid-base homeostasis, provide structure and support for the body, and enable mobility and hearing. Bones come in a variety of shapes and sizes and have complex internal and external structures.

Bone tissue (also known as osseous tissue or bone in the uncountable) is a form of hard tissue, specialised connective tissue that is mineralized and has an intercellular honeycomb-like matrix, which helps to give the bone rigidity. Bone tissue is made up of different types of bone cells: osteoblasts and osteocytes (bone formation and mineralisation); osteoclasts (bone resorption); modified or flattened osteoblasts (lining cells that form a protective layer on the bone surface). The mineralised matrix of bone tissue has an organic component of mainly ossein, a form of collagen, and an inorganic component of bone mineral, made up of various salts. Bone tissue comprises cortical bone and cancellous bone, although bones may also contain other kinds of tissue including bone marrow, endosteum, periosteum, nerves, blood vessels, and cartilage.

An endoskeleton (from Ancient Greek ἔνδον (éndon), meaning "inside", and σκελετός (skeletós), meaning "skeleton") is a structural frame (skeleton) — usually composed of mineralized tissue — on the inside of an animal, overlaid by soft tissues. Endoskeletons serve as structural support against gravity and mechanical loads, and provide anchoring attachment sites for skeletal muscles to transmit force and allow movements and locomotion.

Vertebrates and the closely related cephalochordates are the predominant animal clade with endoskeletons (made of mostly bone and sometimes cartilage, as well as notochordal glycoprotein and collagen fibers), although invertebrates such as sponges also have evolved a form of "rebar" endoskeletons made of diffuse meshworks of calcite/silica structural elements called spicules, and echinoderms have a dermal calcite endoskeleton known as ossicles. Some coleoid cephalopods (squids and cuttlefish) have an internalized vestigial aragonite/calcite-chitin shell known as gladius or cuttlebone, which can serve as muscle attachments but the main function is often to maintain buoyancy rather than to give structural support, and their body shape is largely maintained by hydroskeleton.