Milinda Panha in the context of "Sagala"

Buddhism, a religion founded by Gautama Buddha, first arrived in modern-day Afghanistan through the conquests of Ashoka (r. 268–232 BCE), the third emperor of the Maurya Empire. Among the earliest notable sites of Buddhist influence in the country is a bilingual mountainside inscription in Greek and Aramaic that dates back to 260 BCE and was found on the rocky outcrop of Chil Zena near Kandahar.

Many prominent Buddhist monks were based in Afghanistan during this period: Menander I (r. 165–130 BCE), a Greco-Bactrian king, was a renowned patron of Buddhism and is immortalized in the Milinda Panha, a Pali-language Buddhist text; Mahadharmaraksita, a 2nd-century BCE Indo-Greek monk, is said to have led 30,000 Buddhist monks from "Alasandra, the city of the Yonas" (a colony of Alexander the Great, located approximately 150 kilometres or 93 miles to the north of modern-day Kabul) to Sri Lanka for the dedication of the Mahathupa in Anuradhapura, according to the Mahavamsa (Chap. XXIX); Lokaksema, a 2nd-century Kushan monk, travelled to the Chinese capital city of Luoyang during the reign of the Han dynasty, and was the first translator of Mahayana Buddhist scriptures into the Chinese language.

Suvarṇabhūmi (Sanskrit: सुवर्णभूमि, IPA: [suʋɐrɳɐbʰuːmi]; Pali: Suvaṇṇabhūmi, IPA: [suʋɐɳːɐbʰuːmi]; lit. 'golden land') is a toponym that appears in many ancient Indian literary sources and Buddhist texts such as the Mahavamsa, some of the Jataka tales, the Milinda Panha and the Ramayana.

Though its exact location is unknown and remains a matter of debate, Suvarṇabhūmi was an important port along trade routes that run through the Indian Ocean, setting sail from the wealthy ports in Basra, Ubullah, and Siraf, through Muscat, Malabar, Ceylon, the Nicobars, Kedah and on through the Strait of Malacca to fabled Suvarṇabhūmi.