The Mesopotamia or Región Mesopotámica is the humid and verdant area of northeast Argentina, comprising the provinces of Misiones, Entre Ríos, and Corrientes. The landscape and its characteristics are dominated by two rivers: the Paraná and the Uruguay.
When Spanish settlers came to the area, the two parallel rivers and the lush area between them drew comparisons to Mesopotamia (Greek: Μεσοποταμία "land between rivers") in modern-day Iraq, and it was decided that the Argentine region be named after the Iraqi region. The region shares many of its ecological features with neighboring regions of Argentina and with parts of Brazil, Paraguay, and Uruguay.