Meletius of Antioch (Greek: Μελέτιος, Meletios) was a Christian patriarch of Antioch from 360 until his death in 381. He was opposed by a rival bishop named Paulinus II of Antioch and his episcopate was dominated by the schism, usually called the Meletian schism. As a result, he was exiled from Antioch in 361–362, 365–366 and 371–378. One of his last acts was to preside over the First Council of Constantinople in 381.
There are contrasting views about his theological position: on the one hand, he was exiled three times under Arian emperors; on the other, he was strongly opposed by those faithful to the memory of the staunchly pro-Nicene Eustathius of Antioch, whom the synod of Melitene deposed for his Homoousianism, which they considered a heresy, and by Saint Athanasius of Alexandria, a firm opponent of Arianism.