Measles vaccine in the context of "Lancet MMR autism fraud"

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👉 Measles vaccine in the context of Lancet MMR autism fraud

On 28 February 1998, a fraudulent research paper primarily authored by physician Andrew Wakefield, along with twelve other coauthors (titled "Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children"), was published in The Lancet, a British medical journal. The paper falsely claimed causative links between the measles, mumps, and rubella (MMR) vaccine and colitis, and between colitis and autism. The fraud involved data bias and manipulation, and two undisclosed conflicts of interest. It was exposed in a lengthy Sunday Times investigation by reporter Brian Deer, resulting in the paper's retraction in February 2010 and Wakefield being discredited and struck off the UK medical register three months later. In the paper, Wakefield fabricated evidence to suggest a new "syndrome" existed, which he called "autistic enterocolitis". Wakefield had been employed by a lawyer representing parents in lawsuits against vaccine producers, and had reportedly earned up to US$43 million per year selling diagnostic kits for the non-existent syndrome he claimed to have discovered. He also held a patent to a rival measles vaccine at the time.

The scientific consensus on vaccines and autism is that there is no connection between MMR (or any other vaccine) and autism.

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Measles vaccine in the context of Attenuated vaccine

An attenuated vaccine (or a live attenuated vaccine, LAV) is a vaccine created by reducing the virulence of a pathogen, but still keeping it viable (or "live"). Attenuation takes an infectious agent and alters it so that it becomes harmless or less virulent. These vaccines contrast to those produced by "killing" the pathogen (inactivated vaccine).

Attenuated vaccines stimulate a strong and effective immune response that is long-lasting. In comparison to inactivated vaccines, attenuated vaccines produce a stronger and more durable immune response with a quick immunity onset. They are generally avoided in pregnancy and in patients with severe immunodeficiencies. Attenuated vaccines function by encouraging the body to create antibodies and memory immune cells in response to the specific pathogen which the vaccine protects against. Common examples of live attenuated vaccines are measles, mumps, rubella, yellow fever, varicella, and some influenza vaccines.

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