The Massachusett are a Native American tribe from the region in and around present-day Greater Boston in the Commonwealth of Massachusetts. The name comes from the Massachusett language term for "At the Great Hill," referring to the Blue Hills overlooking Boston Harbor from the south.
As some of the first people to make contact with European explorers in New England, the Massachusett and fellow coastal peoples were severely decimated from an outbreak of leptospirosis circa 1619, which had mortality rates as high as 90 percent in these areas. This was followed by devastating impacts of virgin soil epidemics such as smallpox, influenza, scarlet fever and others to which the Indigenous people lacked natural immunity. Their territories, on the more fertile and flat coastlines, with access to coastal resources, were mostly taken over by English colonists, as the Massachusett were too few in number to put up any effective resistance.
