Marpa Lotsawa in the context of "Naropa"

The Kagyu school, also transliterated as Kagyü, or Kagyud (Tibetan: བཀའ་བརྒྱུད།, Wylie: bka' brgyud), which translates to "Oral Lineage" or "Whispered Transmission" school, is one of the main schools (chos lugs) of Tibetan Buddhism. The Kagyu lineages trace themselves back to the 11th century Indian Mahasiddhas Naropa, Maitripa and the yogini Niguma, via their student Marpa Lotsawa (1012–1097), who brought their teachings to Tibet. Marpa's student Milarepa was also an influential poet and teacher.

The Tibetan Kagyu tradition gave rise to a large number of independent sub-schools and lineages. The principal Kagyu lineages existing today as independent schools are those which stem from Milarepa's disciple, Gampopa (1079–1153), a monk who merged the Kagyu lineage with the Kadam tradition. The Kagyu schools which survive as independent institutions are mainly the Karma Kagyu, Drikung Kagyu, Drukpa Lineage and the Taklung Kagyu. The Karma Kagyu school is the largest of the sub-schools, and is headed by the Karmapa. Other lineages of Kagyu teachings, such as the Shangpa Kagyu, are preserved in other schools.

Maitrīpāda (c.  1007–1085, also known as Maitreyanātha, Advayavajra, and, to Tibetans, Maitrīpa), was a prominent Indian Buddhist Mahasiddha associated with the Mahāmudrā transmission of tantric Buddhism. His teachers were Shavaripa and Naropa. His students include Atisha, Marpa, Vajrapani, Karopa, Natekara (also known as Sahajavajra), Devākaracandra (also known as Śūnyatāsamādhi), and Rāmapāla. His hermitage was in the Mithila region (also known as Tirhut), somewhere in northern Bihar and neighboring parts of southern Nepal.

Jetsun Milarepa (Tibetan: རྗེ་བཙུན་མི་ལ་རས་པ་, Wylie: rje btsun mi la ras pa, 1028/40–1111/23) was a Tibetan siddha, who was famously known as a murderer when he was a young man, before turning to Buddhism and becoming a highly accomplished Buddhist disciple. He is generally considered one of Tibet's most famous yogis and spiritual poets, whose teachings are known among several schools of Tibetan Buddhism. He was a student of Marpa Lotsawa, and a major figure in the history of the Kagyu school of Tibetan Buddhism. He is also famous for the feat of climbing Mount Kailash.

The Shangpa Kagyu (Tibetan: ཤངས་པ་བཀའ་བརྒྱུད, Wylie: shangs pa bka' brgyud, "Oral Tradition of the man from Shang") is known as the "secret lineage" of the Kagyu school of Vajrayana or Tibetan Buddhism and differs in origin from the better known Dagpo Kagyu schools. The Dagpo Kagyu are the lineage of Tilopa through his student Naropa, often traced through Naropa's famous student Marpa Lotsawa and thus called "Marpa Kagyu", while the Shangpa lineage descends from Tilopa's student Niguma, who was Naropa's sister, as well as from the teachings of Sukhasiddhi. Its founder was Khyungpo Naljor, the student of both women, whose monastery in the Shang Valley gave its name to the tradition.

The principal Shangpa dharmapala is the six-armed Mahākāla.