Eumycetoma, also known as Madura foot, is a persistent fungal infection of the skin and the tissues just under the skin, affecting most commonly the feet, although it can occur in hands and other body parts. It starts as a painless wet nodule, which may be present for years before ulceration, swelling, grainy discharge and weeping from sinuses and fistulae, followed by bone deformity.
Many different species of fungi can cause eumycetoma, some examples include: Madurella mycetomatis, Falciformispora senegalensis, Curvularia lunata, Scedosporium species, Acremonium and Fusarium species. Diagnosis is normally done by histopathology and culture. Medical imaging may reveal extent of bone involvement. Other tests include ELISA, immunodiffusion, and Fungal DNA barcoding