M40 motorway in the context of "Slough"

The Oxford to London coach route is an express coach route between Oxford and London along the M40 motorway. Operated by Stagecoach West under the brand name Oxford Tube, there are up to five coaches an hour via Lewknor, High Wycombe Coachway, Hillingdon, Shepherd's Bush and Baker Street terminating on Buckingham Palace Road, Victoria.

The former X90 route, which was operated by the Oxford Bus Company, ran up to two coaches an hour via Baker Street, also terminating on Buckingham Palace Road. This service was withdrawn in January 2020, with the reasons stated being reducing passenger numbers, traffic congestion, and competition from railway services.

In London, the A40 forms a major trunk road starting in the City of London, and passing through six London Boroughs: Camden, Westminster, Kensington & Chelsea, Hammersmith & Fulham, Ealing and Hillingdon, to meet the M40 motorway junction 1 at Denham, Buckinghamshire. Outside London, the road then continues onwards to Fishguard, Wales.

The road has been re-routed several times in the last 100 years – part of the route of the London section of the A40 was laid out in the 1920s and 1930s when Western Avenue was built – now most of it is grade-separated, dual carriageway (divided highway). In the 1960s Westway was constructed, easing traffic access to and from the centre of the city. The A40 links the City of London and the West End to the M40 motorway and M25 motorway. The route is called The London to Fishguard Trunk Road (A40) in legal documents and acts.

The M42 motorway runs north east from Bromsgrove in Worcestershire to just south-west of Ashby-de-la-Zouch in Leicestershire, passing Redditch, Solihull, the National Exhibition Centre (NEC) and Tamworth on the way, serving the east of the Birmingham metropolitan area. The section between the M40 and junction 4 of the M6 forms – though unsigned as such – a part of Euroroute E05. Northwards beyond junction 11, the route is continued as the A42; the junctions on this section, 12–14, are numbered like a continuation of the motorway, but the road has non-motorway status from here.

The A40 is a road which runs between London and Goodwick (Fishguard), in Wales. It is approximately 260 miles (420 km) long. The eastern section from Denham, Buckinghamshire to Wheatley, Oxfordshire is better served by the M40 and its former function of linking London with Cheltenham and Gloucester has been taken by the M4, A419 and A417 via Swindon.

In 1937, together with the A48 road, it formed parts of the London–Fishguard trunk road, as well as a part of the Newport–Shrewsbury trunk road. Much of the A40's length within England has been superseded by motorways, such as the M40, and has lost its trunk road status, though it retains the status west of Gloucester and its entirety within Wales.

Marylebone Road (/ˈmɑːrlɪbən/ MAR-li-bən) is an important thoroughfare in central London, within the City of Westminster. It runs east–west from the Euston Road at Regent's Park to the A40 Westway at Paddington. The road which runs in three lanes in both directions, is part of the London Inner Ring Road and as such forms part of the boundary of the zone within which the London congestion charge applies.

As part of the ring road and a feeder route to the A40 (and hence the M40 motorway) (to the west) and the A5 and M1 motorway (to the north) much of the traffic leaving central London for the Midlands and the North of England travels on this road. It is frequently heavily congested.