Luna 2 in the context of "Moon landing"

The physical exploration of the Moon began when Luna 2, a space probe launched by the Soviet Union, made a deliberate impact on the surface of the Moon on 14 September, 1959. Prior to that the only available means of lunar exploration had been observations from Earth. The invention of the optical telescope brought about the first leap in the quality of lunar observations. Galileo Galilei is generally credited as the first person to use a telescope for astronomical purposes, having made his own telescope in 1609. The mountains and craters on the lunar surface were among his first observations.

Human exploration of the Moon since Luna 2 has consisted of both crewed and uncrewed missions. NASA's Apollo program has been the only program to successfully land humans on the Moon, which it did six times on the near side in the late 20th century. The first human landing took place in 1969, when the Apollo 11 astronauts Buzz Aldrin and Neil Armstrong touched down on the surface in the region of Mare Tranquillitatis, leaving scientific instruments upon the mission's completion and returning lunar samples to Earth. All lunar missions had taken place on the lunar near side until the first soft landing on the far side of the Moon was made by the CNSA robotic spacecraft Chang'e 4 in early 2019, which successfully deployed the Yutu-2 robotic lunar rover. On 25 June 2024, CNSA's Chang'e 6 conducted the first lunar sample return from the far side of the Moon.

Missions to the Moon have been numerous and represent some of the earliest endeavours in space missions, with continuous exploration of the Moon beginning in 1959.

The first partially successful lunar mission was Luna 1 in January 1959, which became the first probe to escape Earth's gravity and perform a flyby of another astronomical body, passing near the Moon. Soon after, the first Moon landing—and the first landing on any extraterrestrial body—was carried out by Luna 2, which intentionally impacted the Moon on 14 September 1959. The far side of the Moon, permanently hidden from Earth due to tidal locking, was imaged for the first time by Luna 3 on 7 October 1959, revealing terrain never before seen.

Sergei Pavlovich Korolev (12 January 1907 [O.S. 30 December 1906] – 14 January 1966) was the lead Soviet rocket engineer and spacecraft designer during the Space Race between the United States and the Soviet Union in the 1950s and 1960s. He invented the R-7 Rocket, Sputnik 1, and was involved in the launching of Laika, Sputnik 3, the first human-made object to make contact with another celestial body, Belka and Strelka, the first human being, Yuri Gagarin, into space, Voskhod 1, and the first person, Alexei Leonov, to conduct a spacewalk.

Although Korolev trained as an aircraft designer, his greatest strengths proved to be in design integration, organization and strategic planning. Arrested on a false official charge as a "member of an anti-Soviet counter-revolutionary organization" (which would later be reduced to "saboteur of military technology"), he was imprisoned in 1938 for almost six years, including a few months in a Kolyma labour camp. Following his release he became a recognized rocket designer and the key figure in the development of the Soviet Intercontinental ballistic missile program. He later directed the Soviet space program and was made a Member of Soviet Academy of Sciences, overseeing the early successes of the Sputnik and Vostok projects including the first human Earth orbit mission by Yuri Gagarin on 12 April 1961. Korolev's unexpected death in 1966 interrupted implementation of his plans for a Soviet crewed Moon landing before the United States 1969 mission.

The Luna programme (from the Russian word Луна "Luna" meaning "Moon"), sometimes called Lunik by western media, was a series of robotic spacecraft missions sent to the Moon by the Soviet Union between 1959 and 1976. The programme accomplished many firsts in space exploration, including first flyby of the Moon, first impact of the Moon and first photos of the far side of the Moon. Each mission was designed as either an orbiter or lander. They also performed many experiments, studying the Moon's chemical composition, gravity, temperature, and radiation.

Twenty-four spacecraft were formally given the Luna designation, although more were launched. Those that failed to reach orbit were not publicly acknowledged at the time, and not assigned a Luna number. Those that failed in low Earth orbit were usually given Cosmos designations. The estimated cost of the Luna programme in 1964 was US$6–10 billion (equivalent to US$46–77 billion in 2024). The Luna 25 mission also continues the Luna designation, although it is considered to be a part of the Luna-Glob exploration programme. The same applies to other planned missions such as Luna 26, Luna 27 and Luna 28.