List of IARC Group 2B carcinogens in the context of "Dichlorodiphenyldichloroethane"

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⭐ Core Definition: List of IARC Group 2B carcinogens

IARC group 2B substances, mixtures and exposure circumstances are those that have been classified as "possibly carcinogenic to humans" by the International Agency for Research on Cancer (IARC) as This category is used when there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals. It may also be used when there is insufficient evidence of carcinogenicity in humans but sufficient evidence in experimental animals. In some cases, an agent, mixture, or exposure circumstance with inadequate evidence of carcinogenicity in humans but limited evidence in experimental animals, combined with supporting evidence from other relevant data, may be included in this group.

This list focuses on the hazard linked to the agents. This means that the carcinogenic agents are capable of causing cancer, but this does not take their risk into account, which is the probability of causing a cancer given the level of exposure to this carcinogenic agent. The list is up to date as of January 2024.

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👉 List of IARC Group 2B carcinogens in the context of Dichlorodiphenyldichloroethane

Dichlorodiphenyldichloroethane (DDD) is an organochlorine insecticide that is slightly irritating to the skin. DDD is a metabolite of DDT. DDD is colorless and crystalline; it is closely related chemically and is similar in properties to DDT, but it is considered to be less toxic to animals than DDT. The molecular formula for DDD is (ClC6H4)2CHCHCl2 or C14H10Cl4, whereas the formula for DDT is (ClC6H4)2CHCCl3 or C14H9Cl5.

DDD is in the “Group B2” classification, meaning that it is a probable human carcinogen. This is based on an increased incidence of lung tumors in male and female mice, liver tumors in male mice, and thyroid tumors in male rats. A further basis is that DDD is similar to and is a metabolite of DDT, another probable human carcinogen.

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List of IARC Group 2B carcinogens in the context of Mobile phone radiation and health

The antennas contained in mobile phones, including smartphones, emit radiofrequency (RF) radiation (non-ionising radiation such as microwaves); the parts of the head or body nearest to the antenna can absorb this energy and convert it to heat or to synchronised molecular vibrations (the term 'heat', properly applies only to disordered molecular motion). Since at least the 1990s, scientists have researched whether the now-ubiquitous radiation associated with mobile phone antennas or cell phone towers is affecting human health. Mobile phone networks use various bands of RF radiation, some of which overlap with the microwave range. Other digital wireless systems, such as data communication networks, produce similar radiation.

In response to public concern, the World Health Organization (WHO) established the International EMF (Electric and Magnetic Fields) Project in 1996 to assess the scientific evidence of possible health effects of EMF in the frequency range from 0 to 300 GHz. They have stated that although extensive research has been conducted into possible health effects of exposure to many parts of the frequency spectrum, all reviews conducted so far have indicated that, as long as exposures are below the limits recommended in the ICNIRP (1998) EMF guidelines, which cover the full frequency range from 0–300 GHz, such exposures do not produce any known adverse health effect. In 2024, the National Cancer Institute wrote: "The evidence to date suggests that cell phone use does not cause brain or other kinds of cancer in humans." In 2011, International Agency for Research on Cancer (IARC), an agency of the WHO, classified wireless radiation as Group 2B – possibly carcinogenic. That means that there "could be some risk" of carcinogenicity, so additional research into the long-term, heavy use of wireless devices needs to be conducted. The WHO states that "A large number of studies have been performed over the last two decades to assess whether mobile phones pose a potential health risk. To date, no adverse health effects have been established as being caused by mobile phone use."

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