La Frontera, Chile in the context of "Toltén River"

The Arauco War was a long-running conflict between colonial Spaniards and the Mapuche people, mostly fought in the Araucanía region of Chile. The conflict began at first as a reaction to the Spanish conquerors attempting to establish cities and force Mapuches into servitude. It subsequently evolved over time into phases comprising drawn-out sieges, slave-hunting expeditions, pillaging raids, punitive expeditions, and renewed Spanish attempts to secure lost territories. Abduction of women and war rape was common on both sides.

The Spaniards penetrated into Mapuche territory during the conquest of Chile until the Battle of Curalaba in 1598 and the following destruction of the Seven Cities led to the establishment of a clear frontier between the Spanish domains and the land of the independent Mapuche. From the 17th to the late 18th century a series of parliaments were held between royal governors and Mapuche lonkos and the war devolved to sporadic pillaging carried out by both sides.

Southern Chile is an informal geographic term for any place south of the capital city, Santiago, or south of Biobío River, the mouth of which is Concepción, about 300 kilometres (200 mi) south of Santiago. Generally cities like Temuco are considered to be located in the south despite being relatively close to the geographical center of Chile. This is mainly because mainland Chile ended in La Frontera until the occupation of Araucanía (1861–1883). Similarly, the Southern Chile wine region is close to the geographic center of the country, encompassing wine-growing areas in the Bío Bío Region and Araucanía Region.

Southern Chile may also refer to the Zona Sur region between Biobío and Chacao Channel, which is often also called the Chilean Lake District. It may also refer to the Zona Austral, also called the Extreme South.