Chiriquí Lagoon is a large lagoon on the northwest coast of Panama covering an area of about 900 square kilometres (350 sq mi). It is separated from the Caribbean Sea by the Valiente Peninsula to the east and from Almirante Bay by islands in the Bocas del Toro Archipelago to the northwest, including Cayo Agua and Isla Popa. The widest and deepest entrance into the bay is the Canal del Tigre in the northeast, which is the main access channel for ships entering the lagoon.
The temperature of the water in the lagoon ranges from 26 to 28 °C. Salinity can be as low as 1.015 (SG) due to runoff from rivers, especially during the rainy season. The mean tidal range is 0.24 metres (9.4 in) with a maximum range of 0.64 metres (2 ft 1 in); tidal flow in the lagoon is weak.