Irene Doukaina in the context of "Theodora Komnene (daughter of Alexios I)"

Isaac II Angelos or Angelus (Greek: Ἰσαάκιος Κομνηνός Ἄγγελος, romanized: Isaákios Komnēnós Ángelos; September 1156 – 28 January 1204) was Byzantine Emperor from 1185 to 1195, and co-Emperor with his son Alexios IV Angelos from 1203 to 1204. In an 1185 revolt against the Emperor Andronikos Komnenos, Isaac seized power and rose to the Byzantine throne, establishing the Angelos family as the new imperial dynasty.

His father Andronikos Doukas Angelos was a military leader in Asia Minor (c. 1122 – aft. 1185) who married Euphrosyne Kastamonitissa (c. 1125 – aft. 1195). Andronikos Doukas Angelos was the son of Constantine Angelos and Theodora Komnene (b. 15 January 1096/1097), the youngest daughter of Emperor Alexios I Komnenos and Irene Doukaina. Thus Isaac was a member of the extended imperial clan of the Komnenoi.

John II Komnenos or Comnenus (Greek: Ἱωάννης ὁ Κομνηνός, romanized: Iōánnēs Komnēnós; 13 September 1087 – 8 April 1143) was Byzantine emperor from 1118 to 1143. Also known as "John the Beautiful" or "John the Good" (Greek: Καλοϊωάννης, romanized: Kaloïōánnēs), he was the eldest son of Emperor Alexios I Komnenos and Irene Doukaina and the second emperor to rule during the Komnenian restoration of the Byzantine Empire. As he was born to a reigning emperor, he had the status of a porphyrogennetos. John was a pious and dedicated monarch who was determined to undo the damage his empire had suffered following the Battle of Manzikert, half a century earlier.

John has been assessed as the greatest of the Komnenian emperors. This view became entrenched due to its espousal by George Ostrogorsky in his influential book History of the Byzantine State, where John is described as a ruler who, "... combined clever prudence with purposeful energy ... and [was] high principled beyond his day." In the course of the quarter-century of his reign, John made alliances with the Holy Roman Empire in the west, decisively defeated the Pechenegs, Hungarians and Serbs in the Balkans, and personally led numerous campaigns against the Turks in Asia Minor. John's campaigns fundamentally changed the balance of power in the east, forcing the Turks onto the defensive; they also led to the recapture of many towns, fortresses and cities across the Anatolian peninsula. In the southeast, John extended Byzantine control from the Maeander in the west all the way to Cilicia and Tarsus in the east. In an effort to demonstrate the Byzantine ideal of the emperor's role as the leader of the Christian world, John marched into Muslim Syria at the head of the combined forces of Byzantium and the Crusader states; yet despite the great vigour with which he pressed the campaign, John's hopes were disappointed by the evasiveness of his Crusader allies and their reluctance to fight alongside his forces.

Anna Dalassene (Greek: Ἄννα Δαλασσηνή; ca. 1025/30 – 1 November 1100/02) was an important Byzantine noblewoman who played a significant role in the rise to power of the Komnenoi in the eleventh century. She exercised great influence over her son, the Emperor Alexios I Komnenos, who gave her the title of empress. She also administered the empire as regent during his many absences from Constantinople on long military campaigns during the early part of his reign. As empress-mother, she exerted more influence and power than the empress-consort, Irene Doukaina, a woman whom she hated because of past intrigues with the Doukai.

John Doukas (or Ducas) (Greek: Ιωάννης Δούκας, Iōannēs Doukas) (died c. 1088) was the son of Andronikos Doukas, a Paphlagonian nobleman who may have served as governor of the theme of Bulgaria (Moesia), and the older brother of Emperor Constantine X Doukas. John Doukas was the paternal grandfather of Irene Doukaina, wife of Emperor Alexios I Komnenos.

He was the original owner of Codex Parisinus graecus 2009, i.e. the oldest known and preserved manuscript of De Administrando Imperio written by Emperor Constantine VII Porphyrogenitus, and copied by one of Doukas' scribes, a well-known encyclopedic Byzantine source on foreign nations from the 10th century.