Indus River in the context of Shigar River

Macedonia (/ˌmæsɪˈdoʊniə/ MASS-ih-DOH-nee-ə; Greek: Μακεδονία, Makedonía), also called Macedon (/ˈmæsɪdɒn/ MASS-ih-don), was an ancient kingdom on the periphery of Archaic and Classical Greece, which later became the dominant state of Hellenistic Greece. The kingdom was founded and initially ruled by the royal Argead dynasty, which was followed by the Antipatrid and Antigonid dynasties. Home to the ancient Macedonians, the earliest kingdom was centred on the northeastern part of the Greek peninsula, and bordered by Epirus to the southwest, Illyria to the northwest, Paeonia to the north, Thrace to the east and Thessaly to the south.

Before the 4th century BC, Macedonia was a small kingdom with its capital at Aigai, outside of the area dominated by the great city-states of Athens, Sparta and Thebes, and briefly subordinate to the Achaemenid Empire. During the reign of the Argead king Philip II (359–336 BC), Macedonia (with its capital at Pella) subdued mainland Greece and the Thracian Odrysian kingdom through conquest and diplomacy. With a reformed army containing phalanxes wielding the sarissa pike, Philip II defeated the old powers of Athens and Thebes in the Battle of Chaeronea in 338 BC. Philip II's son Alexander the Great, leading a federation of Greek states, accomplished his father's objective of commanding the whole of Greece when he destroyed Thebes after the city revolted. During Alexander's subsequent campaign of conquest, he overthrew the Achaemenid Empire and conquered territory that stretched as far as the Indus River. For a brief period, his Macedonian Empire was the most powerful in the world – the definitive Hellenistic state, inaugurating the transition to a new period of Ancient Greek civilization. Greek arts and literature flourished in the new conquered lands and advances in philosophy, engineering, and science spread across the empire and beyond. Of particular importance were the contributions of Aristotle, tutor to Alexander, whose writings became a keystone of Western philosophy.

South Asia is the southern subregion of Asia that is defined in both geographical and ethnic-cultural terms. South Asia, with a population of 2.04 billion, contains a quarter (25%) of the world's population. As commonly conceptualised, the modern states of South Asia include Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri Lanka, with Afghanistan also often included, which may otherwise be classified as part of Central Asia. South Asia borders East Asia to the northeast, Central Asia to the northwest, West Asia to the west and Southeast Asia to the east. Apart from Southeast Asia, Maritime South Asia is the only subregion of Asia that lies partly within the Southern Hemisphere. The British Indian Ocean Territory and two out of 26 atolls of the Maldives in South Asia lie entirely within the Southern Hemisphere. Topographically, it is dominated by the Indian subcontinent and is bounded by the Indian Ocean in the south, and the Himalayas, Karakoram, and Pamir Mountains in the north.

Settled life emerged on the Indian subcontinent in the western margins of the Indus River Basin 9,000 years ago, evolving gradually into the Indus Valley Civilisation of the third millennium BCE. By 1200 BCE, an archaic form of Sanskrit, an Indo-European language, had diffused into India from the northwest, with the Dravidian languages being supplanted in the northern and western regions. By 400 BCE, stratification and exclusion by caste had emerged within Hinduism, and Buddhism and Jainism had arisen, proclaiming social orders unlinked to heredity.

The Achaemenid dynasty (Old Persian: 𐏃𐎧𐎠𐎶𐎴𐎡𐏁𐎡𐎹 Haxāmanišyaʰ; Persian: هخامنشی Haxâmaneši; Ancient Greek: Ἀχαιμενίδαι Achaimenidai; Latin: Achaemenides) was a royal house that ruled the Achaemenid Empire, which eventually stretched from Egypt and the Balkans in the west to Central Asia and the Indus Valley in the east.

Around 535 BCE, the Persian king Cyrus the Great initiated a protracted campaign to absorb parts of India into his nascent Achaemenid Empire. In this initial incursion, the Persian army annexed a large region to the west of the Indus River, consolidating the early eastern borders of their new realm. With a brief pause after Cyrus' death around 530 BCE, the campaign continued under Darius the Great, who began to re-conquer former provinces and further expand the Achaemenid Empire's political boundaries. Around 518 BCE, the Persian army pushed further into India to initiate a second period of conquest by annexing regions up to the Jhelum River in what is today known as Punjab. At peak, the Persians managed to take control of most of modern-day Pakistan and incorporate it into their territory.

The first secure epigraphic evidence through the Behistun Inscription gives a date before or around 518 BCE. Persian penetration into the Indian subcontinent occurred in multiple stages, beginning from the northern parts of the Indus River and moving southward. As mentioned in several Achaemenid-era inscriptions, the Indus Valley was formally incorporated into the Persian realm through provincial divisions: Gandāra, Hindush, and Sattagydia.

India, officially the Republic of India, is a country in South Asia. It is the seventh-largest country by area; the most populous country since 2023; and, since its independence in 1947, the world's most populous democracy. Bounded by the Indian Ocean on the south, the Arabian Sea on the southwest, and the Bay of Bengal on the southeast, it shares land borders with Pakistan to the west; China, Nepal, and Bhutan to the north; and Bangladesh and Myanmar to the east. In the Indian Ocean, India is near Sri Lanka and the Maldives; its Andaman and Nicobar Islands share a maritime border with Myanmar, Thailand, and Indonesia.

Modern humans arrived on the Indian subcontinent from Africa no later than 55,000 years ago. Their long occupation, predominantly in isolation as hunter-gatherers, has made the region highly diverse. Settled life emerged on the subcontinent in the western margins of the Indus river basin 9,000 years ago, evolving gradually into the Indus Valley Civilisation of the third millennium BCE. By 1200 BCE, an archaic form of Sanskrit, an Indo-European language, had diffused into India from the northwest. Its hymns recorded the early dawnings of Hinduism in India. India's pre-existing Dravidian languages were supplanted in the northern regions. By 400 BCE, caste had emerged within Hinduism, and Buddhism and Jainism had arisen, proclaiming social orders unlinked to heredity. Early political consolidations gave rise to the loose-knit Maurya and Gupta Empires. Widespread creativity suffused this era, but the status of women declined, and untouchability became an organised belief. In South India, the Middle kingdoms exported Dravidian language scripts and religious cultures to the kingdoms of Southeast Asia.

The Himalayas, or Himalaya, is a mountain range in Asia separating the plains of the Indian subcontinent from the Tibetan Plateau. The range has some of the Earth's highest peaks, including the highest, Mount Everest. More than 100 peaks exceeding elevations of 7,200 m (23,600 ft) above sea level lie in the Himalayas.

The Himalayas abut on or cross territories of six countries: Nepal, India, China, Bhutan, Pakistan and Afghanistan. The sovereignty of the range in the Kashmir region is disputed among India, Pakistan, and China. The Himalayan range is bordered on the northwest by the Karakoram and Hindu Kush ranges, on the north by the Tibetan Plateau, and on the south by the Indo-Gangetic Plain. Some of the world's major rivers, the Indus, the Ganges, and the Tsangpo–Brahmaputra, rise in the vicinity of the Himalayas, and their combined drainage basin is home to some 600 million people; 53 million people live in the Himalayas. The Himalayas have profoundly shaped the cultures of South Asia and Tibet. Many Himalayan peaks are sacred in Hinduism and Buddhism. The summits of several—Kangchenjunga (from the Indian side), Gangkhar Puensum, Machapuchare, Nanda Devi, and Kailash in the Tibetan Transhimalaya—are off-limits to climbers.

Sir Creek (/sər ˈkrik/ sər KREEK), originally Ban Ganga, is a 96 km (60 mi) tidal estuary in the uninhabited marshlands of the Indus River Delta on the border between India and Pakistan. The creek flows into the Arabian Sea and separates Gujarat state in India from Sindh province in Pakistan. The long-standing India-Pakistan Sir Creek border dispute stems from the demarcation "from the mouth of Sir Creek to the top of Sir Creek, and from the top of Sir Creek eastward to a point on the line designated on the Western Terminus". From this point onward, the boundary is unambiguously fixed as defined by the Tribunal Award of 1968.

Mehrgarh is a Neolithic archaeological site situated on the Kacchi Plain of Balochistan in Pakistan. It is located near the Bolan Pass, to the west of the Indus River and between the modern-day Pakistani cities of Quetta, Kalat and Sibi. The site was discovered in 1974 by the French Archaeological Mission in the Indus Basin led by the French archaeologists Jean-François Jarrige and Catherine Jarrige. Mehrgarh was excavated continuously between 1974 and 1986, and again from 1997 to 2000. Archaeological material has been found in six mounds, and about 32,000 artifacts have been collected from the site. The earliest settlement at Mehrgarh, located in the northeast corner of the 495-acre (2.00 km) site, was a small farming village dated from 7000 BCE or 5250 BCE (see below).

The Indus Valley Civilisation (IVC), also known as the Indus Civilisation, was a Bronze Age civilisation in the northwestern regions of South Asia, lasting from 3300 BCE to 1300 BCE, and in its mature form from 2600 BCE to 1900 BCE. Together with ancient Egypt and Mesopotamia, it was one of three early civilisations of the Near East and South Asia. Of the three, it was the most widespread: it spanned much of Pakistan; northwestern India; and northeast Afghanistan. The civilisation flourished both in the alluvial plain of the Indus River, which flows through the length of Pakistan, and along a system of perennial monsoon-fed rivers that once coursed in the vicinity of the Ghaggar-Hakra, a seasonal river in northwest India and eastern Pakistan.

The term Harappan is also applied to the Indus Civilisation, after its type site Harappa, the first to be excavated early in the 20th century in what was then the Punjab province of British India and is now Punjab, Pakistan. The discovery of Harappa and soon afterwards Mohenjo-daro was the culmination of work that had begun after the founding of the Archaeological Survey of India in the British Raj in 1861. There were earlier and later cultures called Early Harappan and Late Harappan in the same area. The early Harappan cultures were populated from Neolithic cultures, the earliest and best-known of which is named after Mehrgarh, in Balochistan, Pakistan. Harappan civilisation is sometimes called Mature Harappan to distinguish it from the earlier cultures.

The Ghaznavid dynasty (Persian: غزنویان Ġaznaviyān) was a Persianate Muslim dynasty of Turkic mamluk origin. It ruled the Ghaznavid Empire or the Empire of Ghazni from 977 to 1186, which at its greatest extent, extended from the Oxus to the Indus Valley. The dynasty was founded by Sabuktigin upon his succession to the rule of Ghazna after the death of his father-in-law, Alp Tigin, who was an ex-general of the Samanid Empire from Balkh.

Sabuktigin's son, Mahmud of Ghazni, expanded the Ghaznavid Empire to the Amu Darya, the Indus River and the Indian Ocean in the east and to Rey and Hamadan in the west. Under the reign of Mas'ud I, the Ghaznavid dynasty began losing control over its western territories to the Seljuk Empire after the Battle of Dandanaqan in 1040, resulting in a restriction of its holdings to modern-day Afghanistan, Pakistan and Northern India.

The Mughal Empire was an early modern empire in South Asia. At its peak, the empire stretched from the outer fringes of the Indus River Basin in the west, northern Afghanistan in the northwest, and Kashmir in the north, to the highlands of present-day Assam and Bangladesh in the east, and the uplands of the Deccan Plateau in South India.

The Mughal Empire is conventionally said to have been founded in 1526 by Babur, a ruler from what is today Uzbekistan, who employed aid from the neighboring Safavid and Ottoman Empires to defeat the sultan of Delhi, Ibrahim Lodi, in the First Battle of Panipat and to sweep down the plains of North India. The Mughal imperial structure, however, is sometimes dated to 1600, to the rule of Babur's grandson, Akbar. This imperial structure lasted until 1720, shortly after the death of the last major emperor, Aurangzeb, during whose reign the empire also achieved its maximum geographical extent. Reduced subsequently to the region in and around Old Delhi by 1760, the empire was formally dissolved by the British Raj after the Indian Rebellion of 1857.

The Hindu Kush is an 800-kilometre-long (500 mi) mountain range in Central and South Asia to the west of the Himalayas. It stretches from central and eastern Afghanistan into northwestern Pakistan and far southeastern Tajikistan. The range forms the western section of the Hindu Kush Himalayan Region (HKH); to the north, near its northeastern end, the Hindu Kush buttresses the Pamir Mountains to the north near the point where the borders of China, Pakistan and Afghanistan meet, after which it runs southwest through Pakistan and into Afghanistan near their border.

The eastern end of the Hindu Kush merges with the Karakoram Range. Towards its southern end, it connects with the White Mountains near the Kabul River. It divides the valley of the Amu Darya (the ancient Oxus) to the north from the Indus River valley to the south. The range has numerous high snow-capped peaks, with the highest point being Tirich Mir or Terichmir at 7,708 metres (25,289 ft) in the Chitral District of Khyber Pakhtunkhwa, Pakistan.

The Indo-Aryan languages, or sometimes Indic languages, are a branch of the Indo-Iranian languages in the Indo-European language family. As of 2024, there are more than 1.5 billion speakers, primarily concentrated east of the Indus River in Bangladesh, Northern India, Eastern Pakistan, Sri Lanka, Maldives and Nepal. Moreover, apart from the Indian subcontinent, large immigrant and expatriate Indo-Aryan–speaking communities live in Northwestern Europe, Western Asia, North America, the Caribbean, Southeast Africa, Polynesia and Australia, along with several million speakers of Romani languages primarily concentrated in Southeastern Europe. There are over 200 known Indo-Aryan languages.

Modern Indo-Aryan languages descend from Old Indo-Aryan languages such as early Vedic Sanskrit, through Middle Indo-Aryan languages (or Prakrits). The largest such languages in terms of first-speakers are Hindustani (Hindi/Urdu) (c. 330 million), Bengali (242 million), Punjabi (about 150 million), Marathi (112 million), and Gujarati (60 million). A 2005 estimate placed the total number of native speakers of the Indo-Aryan languages at nearly 900 million people. Other estimates are higher, suggesting a figure of 1.5 billion speakers of Indo-Aryan languages.

The history of Islam is believed, by most historians, to have originated with Muhammad's mission in Mecca and Medina at the start of the 7th century CE, although Muslims regard this time as a return to the original faith passed down by the Abrahamic prophets, such as Adam, Noah, Abraham, Moses, David, Solomon, and Jesus, with the submission (Islām) to the will of God. According to the traditional account, the Islamic prophet Muhammad began receiving what Muslims consider to be divine revelations in 610 CE, calling for submission to the one God, preparation for the imminent Last Judgement, and charity for the poor and needy. As Muhammad's message began to attract followers (the ṣaḥāba) he also met with increasing hostility and persecution from Meccan elites. In 622 CE Muhammad migrated to the city of Yathrib (now known as Medina), where he began to unify the tribes of Arabia under Islam, returning to Mecca to take control in 630 and order the destruction of all pagan idols. By the time Muhammad died c. 11 AH (632 CE), almost all the tribes of the Arabian Peninsula had converted to Islam, but disagreement broke out over who would succeed him as leader of the Muslim community during the Rashidun Caliphate.

The early Muslim conquests were responsible for the spread of Islam. By the 8th century CE, the Umayyad Caliphate extended from al-Andalus in the west to the Indus River in the east. Polities such as those ruled by the Umayyad and Abbasid caliphates (in the Middle East and later in Spain and Southern Italy), the Fatimids, Seljuks, Ayyubids, and Mamluks were among the most influential powers in the world. Highly Persianized empires built by the Samanids, Ghaznavids, and Ghurids significantly contributed to technological and administrative developments. The Islamic Golden Age gave rise to many centers of culture and science and produced notable polymaths, astronomers, mathematicians, physicians, and philosophers during the Middle Ages. By the early 13th century, the Delhi Sultanate conquered the northern Indian subcontinent, while Turkic dynasties like the Sultanate of Rum and Artuqids conquered much of Anatolia from the Byzantine Empire throughout the 11th and 12th centuries. In the 13th and 14th centuries, destructive Mongol invasions, along with the loss of population due to the Black Death, greatly weakened the traditional centers of the Muslim world, stretching from Persia to Egypt, but saw the emergence of the Timurid Renaissance and major economic powers such as the Mali Empire in West Africa and the Bengal Sultanate in South Asia. Following the deportation and enslavement of the Muslim Moors from the Emirate of Sicily and elsewhere in southern Italy, the Islamic Iberia was gradually conquered by Christian forces during the Reconquista. Nonetheless, in the early modern period, the gunpowder empires—the Ottomans, Timurids, Mughals, and Safavids—emerged as world powers.

The Indo-Gangetic Plain, also known as the North Indian Plain or the Indus-Gangetic Plain, is a fertile plain spanning 700,000 km (270,000 sq mi) across the northern and north-eastern part of the Indian subcontinent. It encompasses northern and eastern India, eastern Pakistan, southern Nepal, and almost all of Bangladesh. It is named after the two major river systems that drain the region–Indus and Ganges.

It stretches from the Himalayas in the north to the northern edge of the Deccan Plateau in the south, and extends from North East India in the east to the Iranian border in the west. The region is home to many major cities and nearly one-seventh of the world's population. As the region was formed by the deposits of the three major rivers–Indus, Ganges and Brahmaputra, the plains consists of the world's largest expanse of uninterrupted alluvium. Due to its rich water resources, it is one of the world's most densely populated and intensely farmed areas.