Imperial Chemical Industries in the context of "AstraZeneca"

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👉 Imperial Chemical Industries in the context of AstraZeneca

AstraZeneca plc (/ˌæstrəˈzɛnəkə/) (AZ) is a British-Swedish multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge, UK. It has a portfolio of products for major diseases in areas including oncology, cardiovascular, gastrointestinal, infection, neuroscience, respiratory, and inflammation.

The company was founded in 1999 through the merger of the Swedish Astra AB and the British Zeneca Group (itself formed by the demerger of the pharmaceutical operations of Imperial Chemical Industries in 1993). Its portfolio includes primary and speciality care, coverage for rare diseases, and a robust global presence across various regions. Since the merger it has been among the world's largest pharmaceutical companies and has made numerous corporate acquisitions, including Cambridge Antibody Technology (in 2006), MedImmune (in 2007), Spirogen (in 2013) and Definiens (by MedImmune in 2014). It has its research and development concentrated in three strategic centres: Cambridge, UK; Gothenburg, Sweden; and Gaithersburg, Maryland, US.

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Imperial Chemical Industries in the context of Clofibrate

Clofibrate (trade name Atromid-S) is a lipid-lowering agent used for controlling the high cholesterol and triacylglyceride level in the blood. It belongs to the class of fibrates. It increases lipoprotein lipase activity to promote the conversion of VLDL to LDL, and hence reduce the level of VLDL. It can increase the level of HDL as well.

It was patented in 1958 by Imperial Chemical Industries and approved for medical use in 1963. Clofibrate was discontinued in 2002 due to adverse effects.

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Imperial Chemical Industries in the context of Sir Frank Baines

Sir Frank Baines, KCVO, CBE, FRIBA (1877–1933) was chief architect at the British Office of Works from 1920 to 1927.

His most famous work was Thames House and its neighbour Imperial Chemical House (1929–30) in London. Thames House is currently the headquarters of the British Security Service (MI5) and Imperial Chemical House was built as the headquarters for Imperial Chemical Industries (ICI).

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