Heroin in the context of "Pain reliever"

Opium (also known as poppy tears, or Lachryma papaveris) is the dried latex obtained from the seed capsules of the opium poppy Papaver somniferum. Approximately 12 percent of opium is made up of the analgesic alkaloid morphine, which is processed chemically to produce heroin and other synthetic opioids for medicinal use and for the illegal drug trade. Opium's main psychoactive alkaloids, primarily morphine, act on μ-opioid receptors, causing analgesia and addiction with long-term use leading to tolerance, dependence, and increased cancer risk. The latex also contains the closely related opiates codeine and thebaine, and non-analgesic alkaloids such as papaverine and noscapine. The traditional, labor-intensive method of obtaining the latex is to scratch ("score") the immature seed pods (fruits) by hand; the latex leaks out and dries to a sticky yellowish residue that is later scraped off and dehydrated.

The English word for opium is borrowed from Latin, which in turn comes from Ancient Greek: ὄπιον (ópion), a diminutive of ὀπός (opós, "juice of a plant"). The word meconium (derived from the Greek for "opium-like", but now used to refer to newborn stools) historically referred to related, weaker preparations made from other parts of the opium poppy or different species of poppies. The Mediterranean region holds the earliest archaeological evidence of human use of opium poppies dating back to before 5000 BCE, with cultivation beginning around 3400 BCE in Mesopotamia. Opium was widely used for food, medicine, ritual, and as a painkiller throughout ancient civilizations including Greece, Egypt, and Islamic societies up to medieval times.

Drug injection is a method of introducing a drug into the bloodstream via a hollow hypodermic needle, which is pierced through the skin into the body (usually intravenously, but also at an intramuscular or subcutaneous, location). Intravenous therapy, a form of drug injection, is universally practiced in modernized medical care. As of 2004, there were 13.2 million people worldwide who self-administered injection drugs outside of medical supervision, of which 22% are from developed countries.

A wide variety of drugs are injected, often opioids: these may include legally prescribed medicines and medication such as morphine, as well as stronger compounds often favored in recreational drug use, which are often illegal. Ketamine administered intravenously in clinical settings has become more common. Although there are various methods of taking drugs, injection is favoured by some people as the full effects of the drug are experienced very quickly, typically in five to ten seconds. It also bypasses first-pass metabolism in the liver, resulting in higher bioavailability and efficiency for many drugs (such as morphine or diacetylmorphine/heroin; roughly two-thirds of which is destroyed in the liver when consumed orally) than oral ingestion would. The effect is that the person gets a stronger (yet shorter-acting) effect from the same amount of the drug. Drug injection is therefore often related to substance dependence.

The Pruszków mafia (Polish: mafia pruszkowska or gang pruszkowski) was a Polish criminal organization originating from Pruszków in the 1990s and one of the most infamous in the country's modern history. It was active in the vicinity of the city of Warsaw. The group is known for being involved in large car-theft rings, drug trafficking (including cocaine, heroin, hashish and amphetamine), kidnapping, extortion, weapon trafficking (including AK-47s) and murder. Even though law enforcement dealt a severe blow to the organization in 2000 with Jarosław "Masa" Sokołowski taking the stance of crown witness. Despite rumors sparked by the release of a few high-ranking members in 2017 the group has not been significantly active since, with many of the freed bosses re-arrested on subsequent charges. Remnants of the group are thought to be involved in car theft and drug distribution but retain no real influence in the area.

Opioid agonist therapy (OAT) is a treatment in which prescribed opioid agonists are given to patients who live with opioid use disorder (OUD). In the case of methadone maintenance treatment (MMT), methadone is used to treat dependence on heroin or other opioids, and is administered on an ongoing basis.

The benefits of this treatment include a more manageable withdrawal experience, cognitive improvement, and lower HIV transmission. The length of OAT varies from one individual to another based on their physiology, environmental surroundings, and quality of life.

A drug-related crime is a crime to possess, manufacture, or distribute drugs classified as having a potential for abuse (such as cocaine, heroin, morphine and amphetamines). Drugs are also related to crime as drug trafficking and drug production are often controlled by drug cartels, organised crime and gangs. Some drug-related crime involves crime against the person such as robbery or sexual assaults.

A drug test (also often toxicology screen or tox screen) is a technical analysis of a biological specimen, for example urine, hair, blood, breath, sweat, or oral fluid/saliva—to determine the presence or absence of specified parent drugs or their metabolites. Major applications of drug testing include detection of the presence of performance enhancing steroids in sport, employers and parole/probation officers screening for drugs prohibited by law (such as cocaine, methamphetamine, and heroin) and police officers testing for the presence and concentration of alcohol (ethanol) in the blood commonly referred to as BAC (blood alcohol content). BAC tests are typically administered via a breathalyzer while urinalysis is used for the vast majority of drug testing in sports and the workplace. Numerous other methods with varying degrees of accuracy, sensitivity (detection threshold/cutoff), and detection periods exist.

A drug test may also refer to a test that provides quantitative chemical analysis of an illegal drug, typically intended to help with responsible drug use.

Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion.

A subcutaneous injection is administered as a bolus into the subcutis, the layer of skin directly below the dermis and epidermis, collectively referred to as the cutis. The instruments are usually a hypodermic needle and a syringe. Subcutaneous injections are highly effective in administering medications such as insulin, morphine, diacetylmorphine and goserelin. Subcutaneous administration may be abbreviated as SC, SQ, subcu, sub-Q, SubQ, SUBQ, or subcut. SUBQ is the preferred abbreviation to reduce the risk of misunderstanding and potential errors.

Turkish mafia (Turkish: Türk mafyası) is the general term for criminal organizations based in Turkey and/or composed of current or former Turkish citizens. Crime groups with origins in Turkey are active throughout Western Europe (where a strong Turkish immigrant community exists) and less so in the Middle East. Turkish criminal groups participate in a wide range of criminal activities, internationally the most important being drug trafficking, especially heroin. In the trafficking of heroin they cooperate with Bulgarian mafia groups who transport the heroin further to countries such as Italy. Recently however, Turkish mafia groups have also stepped up in the cocaine trafficking world by directly participating in the massive cocaine smuggling pipeline that runs transnationally from South America to Europe. They allegedly have a lucrative partnership with the Venezuelan drug-trafficking organization known as the Cartel of the Suns who ships them cocaine along with criminal elements from Ecuador. Turkish organized crime has pushed into less traditional cocaine markets as well such as into Eastern Europe, the Caucasus, and the wealthy petro-states of the Persian Gulf. Cosa Nostra and the Turkish mafia are also known to be very close. Criminal activities such as the trafficking of other types of drugs, illegal gambling, human trafficking, prostitution or extortion are committed in Turkey itself as well as European countries with a sizeable Turkish community such as Germany, Netherlands, Belgium, Albania, and the United Kingdom.

Most Turkish crime syndicates have their origin in two regions: the Trabzon province on the Black Sea coast of northeastern Turkey and the East and Southeast Anatolia in the south of the country. The biggest origin is on the coast of the Black Sea, located near Trabzon.