Thomas Howard, 5th Duke of Norfolk (9 March 1627 – 13 December 1677) was an English nobleman who from 1645 was deemed a lunatic. Born the eldest son of Henry Howard, 15th Earl of Arundel, Howard left England to study at Utrecht University at the start of the English Civil War. While visiting his paternal grandfather at Padua in 1645 he contracted a fever that damaged his brain. He was declared insane and confined in Padua with a physician caring for his needs. He became Earl of Arundel upon the death of his father in 1652.
Unable to coherently manage his English estates, the running of them was given over to his next eldest brother, Henry Howard, who acted in his place. In 1660 Henry successfully petitioned the House of Lords to have the attainted title Duke of Norfolk restored. Howard, as eldest son in a line descended from Thomas Howard, 4th Duke of Norfolk, became 5th Duke of Norfolk. He never returned to England, being kept at Padua until his death in 1677.