The Guayana natural region (Spanish: Región natural de Guayana), also simply known as Guayana (English: Guiana) in Venezuela, is a large massif of approximately 441,726 km (170,551 sq mi) area, equivalent to 48.2% of the total continental territory of the country.
It is on the geological Guiana Shield craton, and is the Venezuelan part of the biogeographic Guayana Highlands and their tepuis (mesas).