Greco-Bactrian Kingdom in the context of "Bactria"

In classical antiquity, the Hellenistic period covers the time in Greek, Eastern Mediterranean, and West Asian (or Middle Eastern) history following Classical Greece, between the death of Alexander the Great in 323 BC and the death of Cleopatra VII in 30 BC, in which these regions were under the influence of Greek leadership, culture, and language. The Hellenistic period was followed by the ascendancy of the Roman Empire, the Battle of Actium in 31 BC, and the Roman conquest of Ptolemaic Egypt the following year, which eliminated the last major Hellenistic kingdom. Its name stems from the Ancient Greek word Hellas (Ἑλλάς, Hellás), which was gradually recognized as the name for Greece, from which the modern historiographical term Hellenistic was derived. The term "Hellenistic" is to be distinguished from "Hellenic" in that the latter refers to Greece itself, while the former encompasses all the ancient territories of the period that had come under significant Greek influence, particularly the Hellenized Ancient Near East, after the conquests of Alexander the Great.

After the Macedonian conquest of the Achaemenid Empire in 330 BC and its disintegration shortly thereafter in the Partition of Babylon and subsequent Wars of the Diadochi, Hellenistic kingdoms were established throughout West Asia (Seleucid Empire, Kingdom of Pergamon), Northeast Africa (Ptolemaic Kingdom) and South Asia (Greco-Bactrian Kingdom, Indo-Greek Kingdom). This resulted in an influx of Greek colonists and the export of Greek culture and language to these new realms, a breadth spanning as far as modern-day India. These new Greek kingdoms were also influenced by regional indigenous cultures, adopting local practices which were deemed beneficial, necessary, or convenient. Hellenistic culture thus represents a fusion of the ancient Greek world with that of the Western Asian, Northeastern African, and Southwestern Asian worlds. The consequence of this mixture gave rise to a common Attic-based Greek dialect, known as Koine Greek, which became the lingua franca throughout the ancient world.

Afghanistan, officially the Islamic Emirate of Afghanistan, is a landlocked country located at the crossroads of Central and South Asia. It is bordered by Pakistan to the east and south, Iran to the west, Turkmenistan to the northwest, Uzbekistan to the north, Tajikistan to the northeast, and China to the northeast and east. Occupying 652,864 square kilometers (252,072 sq mi) of land, the country is predominantly mountainous with plains in the north and the southwest, which are separated by the Hindu Kush mountain range. Kabul is the country's capital and largest city. Afghanistan's population is estimated to be between 40 and 50 million.

Human habitation in Afghanistan dates to the Middle Paleolithic era. Popularly referred to as the graveyard of empires, the land has witnessed numerous military campaigns, including those by the Persians, Alexander the Great, the Maurya Empire, Arab Muslims, the Mongols, the British, the Soviet Union, and a US-led coalition. Afghanistan also served as the source from which the Greco-Bactrians and the Mughals, among others, rose to form major empires. Because of the various conquests and periods in both the Iranian and Indian cultural spheres, the area was a center for Zoroastrianism, Buddhism, Hinduism, and later Islam. The modern state of Afghanistan began with the Durrani Afghan Empire in the 18th century, although Dost Mohammad Khan is sometimes considered to be the founder of the first modern Afghan state. Afghanistan became a buffer state in the Great Game between the British Empire and the Russian Empire. From India, the British attempted to subjugate Afghanistan but were repelled in the First Anglo-Afghan War; the Second Anglo-Afghan War saw a British victory. Following the Third Anglo-Afghan War in 1919, Afghanistan became free of foreign political hegemony, and emerged as the independent Kingdom of Afghanistan in 1926. This monarchy lasted almost half a century, until Zahir Shah was overthrown in 1973, following which the Republic of Afghanistan was established.

Tajikistan, officially the Republic of Tajikistan, is a landlocked country in Central Asia. Dushanbe is its capital and most populous city. Tajikistan borders Afghanistan to the south, Uzbekistan to the west, Kyrgyzstan to the north, and China to the east and is narrowly separated from Pakistan by Afghanistan's Wakhan Corridor. It has a population of more than 10.7 million people.

The territory was previously home to cultures of the Neolithic and the Bronze Age, including the Oxus civilisation in west, with the Indo-Iranians arriving during the Andronovo culture. Parts of country were part of the Sogdian and Bactrian civilisations, and was ruled by those including the Achaemenids, Alexander the Great, the Greco-Bactrians, the Kushans, the Kidarites and Hephthalites, the First Turkic Khaganate, the Umayyad and Abbasid Caliphates, the Samanid Empire, the Kara-Khanids, Seljuks, Khwarazmians, the Mongols, Timurids and Khanate of Bukhara. The region was later conquered by the Russian Empire, before becoming part of the Soviet Union. Within the Soviet Union, the country's borders were drawn when it was part of Uzbekistan as an autonomous republic before becoming a constituent republic of the Soviet Union on 5 December 1929.

Uzbekistan, officially the Republic of Uzbekistan, is a doubly landlocked country located in Central Asia. It is surrounded by five countries: Kazakhstan to the north, Kyrgyzstan to the northeast, Tajikistan to the southeast, Afghanistan to the south, and Turkmenistan to the southwest, making it one of only two doubly landlocked countries on Earth, the other being Liechtenstein. The country has a population of more than 37.6 million, making it the most populous country in Central Asia. Uzbekistan is a member of the Organization of Turkic States. Uzbek, spoken by the Uzbek people, is the official language and spoken by the majority of its inhabitants, while Russian and Tajik are significant minority languages. Islam is the predominant religion, and most Uzbeks are Sunni Muslims.

The first recorded settlers in the land of what is contemporary Uzbekistan were Eastern Iranian nomads, known as Scythians, who founded kingdoms in Khwarazm, Sogdiana, and Bactria in the 8th–6th centuries BC, as well as Fergana and Margiana in the 3rd century BC – 6th century AD. The area was incorporated into the Achaemenid Empire and, after a period of Greco-Bactrian rule and later by the Sasanian Empire, until the Muslim conquest of Persia in the seventh century. The early Muslim conquests and the subsequent Samanid Empire converted most of the people into adherents of Islam. During this period, cities began to grow rich from the Silk Road, and became a center of the Islamic Golden Age. The local Khwarazmian dynasty was destroyed by the Mongol invasion in the 13th century, leading to a dominance by Mongol peoples. Timur in the 14th century established the Timurid Empire. Its capital was Samarkand, which became a center of science under the rule of Ulugh Beg, giving birth to the Timurid Renaissance. The territories of the Timurid dynasty were conquered by Kipchak Shaybanids in the 16th century. Conquests by Emperor Babur towards the east led to the foundation of the Mughal Empire in India. Most of Central Asia was gradually incorporated into the Russian Empire during the 19th century, with Tashkent becoming the political center of Russian Turkestan. In 1924, national delimitation created the Uzbek Soviet Socialist Republic as a republic of the Soviet Union. It declared independence as the Republic of Uzbekistan in 1991.

The ancient history of Afghanistan, also referred to as the pre-Islamic period of Afghanistan, dates back to the prehistoric era and the Helmand civilization around 3300–2350 B.C. Archaeological exploration began in Afghanistan in earnest after World War II and proceeded until the late 1970s during the Soviet–Afghan War. Archaeologists and historians suggest that humans were living in Afghanistan at least 50,000 years ago, and that farming communities of the region were among the earliest in the world. Urbanized culture has existed in the land from between 3000 and 2000 BC. Artifacts typical of the Paleolithic, Mesolithic, Neolithic, Bronze, and Iron ages have been found inside Afghanistan.

After the Indus Valley Civilisation stretched up to northeast Afghanistan, it was inhabited by the Iranic tribes and controlled by the Medes until about 500 BC when Darius the Great (Darius I) marched with his Persian army to make it part of the Achaemenid Empire. In 330 BC, Alexander the Great of Macedonia invaded the land after defeating Darius III of Persia in the Battle of Gaugamela. Much of Afghanistan became part of the Seleucid Empire followed by the Greco-Bactrian Kingdom. Seleucus I Nicator was defeated by Chandragupta Maurya and gave his daughter in a peace treaty. The land was inhabited by various tribes and ruled by many different kingdoms for the next two millennia. Before the arrival of Islam in the 7th century, there were a number of religions practiced in modern-day Afghanistan. Zoroastrianism and Ancient Iranian religions were practiced in western Afganistan (Khorasan and Herat). Hinduism and Buddhism was primarily practiced in regions of Eastern (Kabul) and South-Eastern Afganistan (Kandahar). The Kafiristan (present-day Nuristan) region, in the Hindu Kush mountain range, was not converted until the 19th century. They still follow the ancient Vedic religion (related to modern day Hinduism).