Golden Gate in the context of "Golden Gate Bridge"

San Francisco, officially the City and County of San Francisco, is a commercial, financial, and cultural center of Northern California. With an estimated population of 827,526 residents as of 2024, San Francisco proper is the fourth-most populous city in the U.S. state of California and the 17th-most populous in the United States. Among U.S. cities proper with over 300,000 residents, San Francisco is ranked second by population density, first by per capita income, and sixth by aggregate income as of 2023. Depending on how its borders are defined, the broader San Francisco metropolitan area or San Francisco Bay Area is home to 4.6–9.2 million residents. In 2024, the U.S. Census Bureau reported an estimated population of 4,648,486 for the city's metropolitan statistical area (13th-largest in the U.S.) and 9,164,058 residents for the larger combined statistical area (5th-largest).

Prior to European settlement, the modern city proper was inhabited by the Yelamu Ohlone. On June 29, 1776, settlers from New Spain established the Presidio of San Francisco at the Golden Gate, and the Mission San Francisco de Asís a few miles away, both named for Francis of Assisi. The California gold rush of 1849 brought rapid growth, making it the largest city on the West Coast at the time. In 1856, San Francisco became a consolidated city-county. After three-quarters of the city was destroyed by the 1906 earthquake and fire, it was quickly rebuilt, hosting the Panama–Pacific International Exposition nine years later. In World War II, it was a major port of embarkation for naval service members shipping out to the Pacific Theater. After the war, the confluence of returning servicemen, significant immigration, liberalizing attitudes, the rise of the beatnik and hippie countercultures, the sexual revolution, opposition to U.S. involvement in the Vietnam War, and other factors led to the Summer of Love and the gay rights movement, cementing San Francisco as a center of liberal activism.

San Francisco Bay is a large tidal estuary in the U.S. state of California, and gives its name to the San Francisco Bay Area. It is dominated by the cities of San Francisco, San Jose, and Oakland.

San Francisco Bay drains water from approximately 40 percent of California. Water from the Sacramento and San Joaquin rivers, and from the Sierra Nevada mountains, flow into Suisun Bay, which then travels through the Carquinez Strait to meet with the Napa River at the entrance to San Pablo Bay, which connects at its south end to San Francisco Bay. It then connects to the Pacific Ocean via the Golden Gate strait. However, this entire group of interconnected bays is often called San Francisco Bay. The bay was designated a Ramsar Wetland of International Importance on February 2, 2013, and the Port of Oakland on the bay is one of the busiest cargo ports on the west coast.

The port of San Francisco is a semi-independent organization that oversees the port facilities at San Francisco, California, United States. It is run by a five-member commission, appointed by the mayor subject to confirmation by a majority of the board of supervisors. The Port is responsible for managing the larger waterfront area that extends from the anchorage of the Golden Gate Bridge, along the Marina district, all the way around the north and east shores of the city of San Francisco including Fisherman's Wharf and the Embarcadero, and southward to the city line just beyond Candlestick Point. In 1968, the State of California, via the California State Lands Commission for the state-operated San Francisco Port Authority (est. 1957), transferred its responsibilities for the Harbor of San Francisco waterfront to the City and County of San Francisco/San Francisco Harbor Commission through the Burton Act AB2649. All eligible state port authority employees had the option to become employees of the City and County of San Francisco to maintain consistent operation of the port of San Francisco.

The port of San Francisco lies on the western edge of the San Francisco Bay near the Golden Gate. It has been called one of the three great natural harbors in the world, but it took two long centuries for navigators from Spain and England to find the anchorage originally called Yerba Buena: a port, as was said in its early days, in which all the fleets of the world could find anchorage.

U.S. Route 101 (US 101) is a major north–south United States Numbered Highway, stretching from Los Angeles, California, to Tumwater, Washington. The California portion of US 101 is one of the last remaining and longest U.S. Routes still active in the state, and the longest highway of any kind in California. US 101 was also one of the original national routes established in 1926. Significant portions of US 101 between the Los Angeles area and the San Francisco Bay Area follow El Camino Real, the commemorative route connecting the former Alta California's 21 missions.

Although the highway has been superseded in overall importance for transportation through the state by Interstate 5 (I-5), US 101 continues to be the major coastal north–south route that links the Greater Los Angeles Area, the Central Coast, the San Francisco Bay Area, and the North Coast (Redwood Empire). Generally referred to as "101" by residents of Northern California, in Southern California it is often called "The 101" (pronounced "the one oh one"). The highway has portions designated as the Santa Ana Freeway, the Hollywood Freeway, the Ventura Freeway, South Valley Freeway, and Bayshore Freeway, as well as El Camino Real in many non-freeway segments. The Redwood Highway, the 350-mile-long (560 km) northernmost segment of the highway, begins at the Golden Gate and passes through the world's tallest and only extensive preserves of virgin, old-growth coast redwood trees.

Alcatraz Island (/ˈælkəˌtræz/) is a small island about 1.25 miles offshore from San Francisco in San Francisco Bay, California, near the Golden Gate Strait. The island was developed in the mid-19th century with facilities for a lighthouse, a military fortification, and a military prison. In 1934, the island was converted into a federal prison, Alcatraz Federal Penitentiary. The strong tidal currents around the island and ice-cold water temperatures made escape nearly impossible, giving the prison one of the most notorious reputations of its kind in American history. The prison closed on March 21, 1963, leaving the island a major tourist attraction today with nearly 1.4 million people visiting the island annually.

Beginning in November 1969, the island was occupied for more than 19 months by a group of Native Americans, initially primarily from San Francisco, who were later joined by the American Indian Movement and other urban Native Americans from other parts of the country, who were part of a wave of Native American activists organizing public protests across the US through the 1970s. In 1972, Alcatraz was transferred to the Department of Interior to become part of Golden Gate National Recreation Area. It was designated as a National Historic Landmark in 1986.