Glutamate—cysteine ligase in the context of "Glutathione"

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👉 Glutamate—cysteine ligase in the context of Glutathione

Glutathione (GSH, /ˌɡltəˈθn/) is an organic compound made of the amino acids glutamate, cysteine, and glycine. It is an antioxidant in plants, animals, fungi, and some bacteria and archaea. Glutathione is capable of preventing damage to important cellular components caused by sources such as reactive oxygen species, free radicals, peroxides, lipid peroxides, and heavy metals. It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and cysteine. The carboxyl group of the cysteine residue is attached by normal peptide linkage to glycine.

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