Georgios Nikolaou Papanikolaou (or George Papanicolaou /ˌpæpəˈnɪkəlaʊ/; Greek: Γεώργιος Ν. Παπανικολάου [papanikoˈlau]; 13 May 1883 – 19 February 1962) was a Greek physician, zoologist and microscopist who was a pioneer in cytopathology and early cancer detection, and inventor of the pap smear for detection of cervical cancer.
After studying medicine in Greece and Germany, in 1913 he emigrated to the United States and was on the faculty at Cornell Medical College. He first reported that uterine cancer cells could be detected in vaginal smears in 1928, but his work was not widely recognized until the 1940s. An extensive trial of his techniques was carried out in the early 1950s. In 1961 he was invited to the University of Miami to lead and develop there the Papanicolaou Cancer Research Institute.
