Generalbezirk Lettland (German for "General District Latvia"; Latvian: Latvijas ģenerālapgabals) was an administrative subdivision of the Reichskommissariat Ostland of Nazi Germany that covered Latvia from 1941 to 1944. It served as the Nazi civilian administration for the German occupation of Latvia during World War II, and supervised the collaborationist Latvian Self-Administration of Oskars Dankers.
Otto-Heinrich Drechsler was the only Generalkommissar of Generalbezirk Lettland during its existence.