Fruit flies in space in the context of "Albert II (monkey)"

Animals in space originally served to test the survivability of spaceflight, before human spaceflights were attempted. Later, many species were flown to investigate various biological processes and the effects microgravity and space flight might have on them. Bioastronautics is an area of bioengineering research that spans the study and support of life in space. To date, seven national space programs have flown non-human animals into space: the United States, Soviet Union, France, Argentina, China, Japan and Iran.

A wide variety of non-human animals have been launched into space, including monkeys and apes, dogs, cats, tortoises, mice, rats, rabbits, fish, frogs, spiders, insects, and quail eggs (which hatched on Mir in 1990). The US launched the first Earthlings into space, with fruit flies surviving a 1947 flight, followed by primates in 1949. The Soviet space program launched multiple dogs into space, with the first sub-orbital flights in 1951, and first orbital flights in 1957.

Drosophila melanogaster is a species of fly (an insect of the order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly", "pomace fly", or "banana fly". In the wild, D. melanogaster are attracted to rotting fruit and fermenting beverages, and they are often found in orchards, kitchens and pubs.

Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, D. melanogaster continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. In 1946 D. melanogaster was the first animal to be launched into space. As of 2017, six Nobel Prizes have been awarded to drosophilists for their work using the insect.