Vendsyssel (Danish pronunciation: [ˈvenˌsysl̩]) is the northernmost traditional district of Denmark and of Jutland. Being divided from mainland Jutland by the Limfjord, it is technically a part of the North Jutlandic Island which also comprises the areas Hanherred and Thy. Vendsyssel is part of the North Denmark Region.
Vendsyssel neighbours Hanherred to the southwest and Himmerland to the south, across the Limfjord. Whether the island Læsø is also a part of Vendsyssel, is a matter of definition. The major towns of Vendsyssel are Hjørring, Frederikshavn, Brønderslev, Sæby, Hirtshals, Løkken, Nørresundby and, on its northern tip, Skagen. The dominating city is, however, Aalborg which is mainly situated outside Vendsyssel on the southern shore of the Limfjord with Nørresundby as a secondary, northern centre.