Dera Ghazi Khan (Urdu: ضلع ڈيره غازى خان, Saraiki: ضلع دیرہ غازی خان) is a district in Punjab, Pakistan. Its administrative capital is Dera Ghazi Khan.
The district lies to the west of the Indus River. The Sulaiman Mountains rise to a height of 10,000 feet (3,000 m) in the north of the district. Popular tourist destinations are Fort Munro, Yakbai Hill station and Mubarki Top.