Etiology in the context of Behaviour genetics

Psychopathology is the study of mental illness. It includes the signs and symptoms of all mental disorders. The field includes abnormal cognition, maladaptive behavior, and experiences which differ according to social norms. This discipline is an in-depth look into symptoms, behaviors, causes, course, development, categorization, treatments, strategies, and more.

Biological psychopathology is the study of the biological etiology of abnormal cognitions, behaviour and experiences. Child psychopathology is a specialization applied to children and adolescents.

Jews originated from the Israelites and Hebrews of historical Israel and Judah, two related kingdoms that emerged in the Levant during the Iron Age. The earliest mention of Israelites is inscribed on the Merneptah Stele c. 1213–1203 BCE; later religious literature tells the story of Israelites going back at least as far as c. 1500 BCE. Traditionally, the name Israel is said to originate with the Hebrew patriarch Jacob, who provides a narrative etiology for the name – after wrestling with an angel, Jacob is renamed Israel, meaning "he who struggles with God". The Kingdom of Israel based in Samaria fell to the Neo-Assyrian Empire c. 720 BCE, and the Kingdom of Judah to the Neo-Babylonian Empire in 586 BCE. Part of the Judean population was exiled to Babylon. The Assyrian and Babylonian captivities are regarded as representing the start of the Jewish diaspora.

After the Achaemenid Empire conquered the region, the exiled Jews were allowed to return and rebuild the temple; these events mark the beginning of the Second Temple period. After several centuries of foreign rule, the Maccabean Revolt against the Seleucid Empire led to an independent Hasmonean kingdom, but it was gradually incorporated into the Roman imperial system. The Jewish–Roman wars, a series of unsuccessful revolts against the Romans in the 1st and 2nd centuries CE, resulted in the destruction of Jerusalem and the Second Temple, and the expulsion of many Jews. The Jewish population in Syria Palaestina gradually decreased during the following centuries, enhancing the role of the Jewish diaspora and shifting the spiritual and demographic centre from the depopulated Judea to Galilee and then to Babylon, with smaller communities spread out across the Roman Empire. During the same period, the Mishnah and the Talmud, central Jewish texts, were composed. In the following millennia, the diaspora communities coalesced into three major ethnic subdivisions according to where their ancestors settled: the Ashkenazim in Central and Eastern Europe, the Sephardim initially in Iberia, and the Mizrahim in the Middle East and North Africa.

Criminology (from Latin crimen, 'accusation', and Ancient Greek -λογία, -logia, from λόγος logos, 'word, reason') is the interdisciplinary study of crime and deviant behaviour. Criminology is a multidisciplinary field in both the behavioural and social sciences, which draws primarily upon the research of sociologists, political scientists, economists, legal sociologists, psychologists, philosophers, psychiatrists, social workers, biologists, social anthropologists, scholars of law and jurisprudence, as well as the processes that define administration of justice and the criminal justice system.

The interests of criminologists include the study of the nature of crime and criminals, origins of criminal law, etiology of crime, social reaction to crime, and the functioning of law enforcement agencies and the penal institutions. It can be broadly said that criminology directs its inquiries along three lines: first, it investigates the nature of criminal law and its administration and conditions under which it develops; second, it analyzes the causation of crime and the personality of criminals; and third, it studies the control of crime and the rehabilitation of offenders. Thus, criminology includes within its scope the activities of legislative bodies, law-enforcement agencies, judicial institutions, correctional institutions and educational, private and public social agencies.

Peyronie's disease (PD) is a benign, acquired penile connective tissue disease characterized by the occurrence of fibrotic plaques within the tunica albuginea — the dense elastic covering of the corpora cavernosa. The plaques cause abnormal curvature, pain, penile deformities (e.g., narrowing or indentation), and usually erectile dysfunction, particularly during erection. The condition typically leads to significant sexual and psychological effects, including difficulty with penetration and lowered self-esteem or evasiveness. Peyronie's disease is most often seen in middle-aged and older men with a median age of onset between 55 and 60 years, however it is also common in younger individuals and adolescents.

While the etiology of Peyronie's disease is still uncertain, the leading hypothesis is that it arises from dysregulated wound healing in response to chronic microtrauma of the erect penis. This triggers a cascade of profibrotic molecular pathways — most notably overexpression of transforming growth factor-beta 1 (TGF-β1) — that end in fibroblast proliferation, myofibroblast differentiation, and overproduction of type I collagen. Genetic predisposition is supported by family clustering and linkage with systemic fibrosing disorders such as Dupuytren's contracture. Risk factors include age, penile injury, diabetes mellitus, and cigarette smoking.

Zanclus (Ancient Greek: Ζάγκλος) is the legendary first king of the Sicilian city of Messina. He is mentioned in an etiological passage by Diodorus of Sicily, and has become a symbol of Messina. In modern Italian, the form is given as Zanclo.

Gegenus is recorded as the father of Zanclus. Diodorus writes of Zanclus as the supposed eponym of "Zancle" (Ancient Greek: Ζάγκλη, romanized: Zágklē) (the ancient name for Messina). The giant Orion is said to have helped Zanclus in building the city and the harbor.

Biological psychopathology is the study of the biological etiology of mental illnesses with a particular emphasis on the genetic and neurophysiological basis of clinical psychology. Biological psychopathology attempts to explain psychiatric disorders using multiple levels of analysis from the genome to brain functioning to behavior. Although closely related to clinical psychology, it is fundamentally an interdisciplinary approach that attempts to synthesize methods across fields such as neuroscience, psychopharmacology, biochemistry, genetics, and physiology. It is known by several alternative names, including "clinical neuroscience" and "experimental psychopathology." Due to the focus on biological processes of the central and peripheral nervous systems, biological psychopathology has been important in developing new biologically-based treatments for mental disorders.

Plant pathology or phytopathology is the scientific study of plant diseases caused by pathogens (infectious organisms) and environmental conditions (physiological factors). Plant pathology involves the study of pathogen identification, disease etiology, disease cycles, economic impact, plant disease epidemiology, plant disease resistance, how plant diseases affect humans and animals, pathosystem genetics, and management of plant diseases.

Behavioural genetics, also referred to as behaviour genetics, is a field of scientific research that uses genetic methods to investigate the nature and origins of individual differences in behaviour. While the name "behavioural genetics" connotes a focus on genetic influences, the field broadly investigates the extent to which genetic and environmental factors influence individual differences, and the development of research designs that can remove the confounding of genes and environment.

Behavioural genetics was founded as a scientific discipline by Francis Galton in the late 19th century, only to be discredited through association with eugenics movements before and during World War II. In the latter half of the 20th century, the field saw renewed prominence with research on inheritance of behaviour and mental illness in humans (typically using twin and family studies), as well as research on genetically informative model organisms through selective breeding and crosses. In the late 20th and early 21st centuries, technological advances in molecular genetics made it possible to measure and modify the genome directly. This led to major advances in model organism research (e.g., knockout mice) and in human studies (e.g., genome-wide association studies), leading to new scientific discoveries.

Mordecai (/ˈmɔːrdɪkaɪ, mɔːrdɪˈkeɪaɪ/; also Mordechai; Hebrew: מָרְדֳּכַי, Modern: Mŏrdoḵay, Tiberian: Mārdoḵay, IPA: [moʁdeˈχaj]) is one of the main personalities in the Book of Esther in the Hebrew Bible. He is the cousin and guardian of Esther, who became queen of Persia under the reign of Ahasuerus (Xerxes I). Mordecai's loyalty and bravery are highlighted in the story as he helps Esther foil the plot of Haman, the king's vizier, to exterminate the Jewish people. His story is celebrated in the Jewish holiday of Purim, which commemorates his victory.

One theory frequently discussed in scholarship suggests that the Book of Esther serves as an etiology for Purim, with Mordecai and Esther representing the Babylonian gods Marduk and Ishtar in a historicized Babylonian myth or ritual. The identification of Mordecai with a Persian official named "Marduka" mentioned in an inscription from the reign of Xerxes I is debated, with some scholars rejecting the connection while others support it due to the commonality of name and office. Even if the Marduka who was mentioned in the inscription was not Mordecai himself it shows the name was in use during that period.

Causal inference is the process of determining the independent, actual effect of a particular phenomenon that is a component of a larger system. The main difference between causal inference and inference of association is that causal inference analyzes the response of an effect variable when a cause of the effect variable is changed. The study of why things occur is called etiology, and can be described using the language of scientific causal notation. Causal inference is said to provide the evidence of causality theorized by causal reasoning.

Causal inference is widely studied across all sciences. Several innovations in the development and implementation of methodology designed to determine causality have proliferated in recent decades. Causal inference remains especially difficult where experimentation is difficult or impossible, which is common throughout most sciences.

Zebulun (Hebrew: זְבֻלוּן/זְבוּלֻן/זְבוּלוּן, Modern: Zəvūlūn, Tiberian: Zăḇūlūn; also Zebulon, Zabulon, or Zaboules in Antiquities of the Jews by Josephus) was, according to the Books of Genesis and Numbers, the last of the six sons of Jacob and Leah (Jacob's tenth son), and the founder of the Israelite tribe of Zebulun. Some biblical scholars believe this to be an eponymous metaphor providing an etiology of the connectedness of the tribe to others in the Israelite confederation. With Leah as a matriarch, biblical scholars believe the tribe to have been regarded by the text's authors as a part of the original Israelite confederation.

The Tomb of Zebulun is located in Sidon, Lebanon. In the past, towards the end of Iyyar, Jews from the most distant parts of the land of Israel would make a pilgrimage to this tomb.

Symptomatic treatment, supportive care, supportive therapy, or palliative treatment is any medical therapy of a disease that only affects its symptoms, not the underlying cause. It is usually aimed at reducing the signs and symptoms for the comfort and well-being of the patient, but it also may be useful in reducing organic consequences and sequelae of these signs and symptoms of the disease. In many diseases, even in those whose etiologies are known (e.g., most viral diseases, such as influenza and Rift Valley fever), symptomatic treatment is the only treatment available so far.

For more detail, see supportive therapy. For conditions like cancer, arthritis, neuropathy, tendinopathy, and injury, it can be useful to distinguish treatments that are supportive/palliative and cannot alter the natural history of the disease (disease modifying treatments).