Ebussuud Efendi (Turkish: Mehmed Ebüssuûd Efendi, 30 December 1490 – 23 August 1574), was a Hanafi Maturidi Ottoman jurist and Quran exegete, served as the Qadi (judge) of Istanbul from 1533 to 1537, and the Shaykh al-Islām of the Ottoman Empire from 1545 to 1574. He was also called "El-İmâdî" because his family hailed from Imâd, a village near İskilip.
Ebussuud was the son of Iskilipli Sheikh Muhiddin Muhammad Efendi. In the 1530s, Ebussuud served as a judge in Bursa, Istanbul and Rumelia, where he brought local laws into conformity with Islamic divine law (sharia). Sultan Suleiman the Magnificent promoted him to Shaykh al-Islām – the supreme judge and highest official – in 1545, an office Ebussuud held until his death and which he brought to the peak of its power. He worked closely with the Sultan, issuing judicial opinions that legitimised Suleiman's killings of Yazidis and his successor Selim's attack on Cyprus. Ebussuud also issued legal rulings (fatwās) which labeled the Qizilbash, regardless of whether they lived on Iranian or Ottoman soil, as "heretics", and declared that killing them would be viewed as praiseworthy, rather than just being allowed according to the law.