De materia medica (Latin name for the Greek work Περὶ ὕλης ἰατρικῆς, Peri hulēs iatrikēs, both meaning "On Medical Material") is a pharmacopoeia of medicinal plants and the medicines that can be obtained from them. The five-volume work was written between 50 and 70 CE by Pedanius Dioscorides, a Greek physician in the Roman army. It was widely read for more than 1,500 years until supplanted by revised herbals in the Renaissance, making it one of the longest-lasting of all natural history and pharmacology books.
The work describes many drugs known to be effective, including aconite, aloes, colocynth, colchicum, henbane, opium and squill. In total, about 600 plants are covered, along with some animals and mineral substances, and around 1000 medicines made from them.