The Struma Motorway (Bulgarian: Автомагистрала „Струма“, Avtomagistrala "Struma") is a motorway currently under construction in Bulgaria. The motorway is located in the Yugozapaden area in South West Bulgaria, and follows the route Sofia-Pernik-Dupnitsa-Blagoevgrad-Sandanski to Kulata on the border with in Greece. It is part of the Pan-European Corridor IV and also is part of Е79, that runs from Miskolc (Hungary) to Thessaloniki (Greece), via the Romanian cities of Deva and Craiova. This project is under the European Union's Ten-T Priority Projects. The road is also part of the proposed Via Carpatia route.
The Struma motorway forms a connection between Sofia and Kulata at the Bulgaria-Greece border with a total planned length of 172.8 km. As of February 2024, about 143km. of the motorway, from Sofia to Blagoevgrad, and from Kresna to Kulata have already been completed and are in service.