The County of Edessa (Latin: Comitatus Edessanus) was a 12th-century Crusader state in Upper Mesopotamia. Its seat was the city of Edessa (modern Şanlıurfa, Turkey).
In the late Byzantine period, Edessa became the centre of intellectual life within the Syriac Orthodox Church. As such it also became the centre for the translation of Ancient Greek philosophy into Syriac, which provided a stepping stone for the subsequent translations into Arabic. When the crusades arrived, it was still important enough to tempt a side-expedition after the siege of Antioch.