Count of Vendôme and, later, Duke of Vendôme were titles of French nobility. The first-known holder of the comital title was Bouchard Ratepilate. The county passed by marriage to various houses, coming in 1372 to a junior branch of the House of Bourbon. In 1514, Vendôme was made a duchy-peerage.
In 1589, the then Duke of Vendôme came to the throne as Henry IV of France, and the title passed into the royal domain. It was re-granted to his illegitimate son César in 1598, and held by his descendants until the extinction of the legitimate male line in 1727.