Convalescence in the context of "Illness"

A sanatorium (from Latin sānāre 'to heal'), also sanitarium or sanitorium, is a historic name for a specialised hospital for the treatment of specific diseases, related ailments, and convalescence.

Sanatoria were often in a healthy climate, usually in the countryside. The idea of healing was an important reason for the historical wave of establishments of sanatoria, especially at the end of the 19th and early 20th centuries. The most common issue treated at sanatoria was tuberculosis (before the discovery of antibiotics). Some sanatoria also treated alcoholism as well as hysteria, masturbation, fatigue and emotional exhaustion. Facility operators were often charitable associations, such as the Order of St. John and the newly founded social welfare insurance companies.

Experimental autoimmune encephalomyelitis, sometimes experimental allergic encephalomyelitis (EAE), is an animal model of brain inflammation. It is an inflammatory demyelinating disease of the central nervous system (CNS). It is mostly used with rodents and is widely studied as an animal model of the human CNS demyelinating diseases, including multiple sclerosis (MS) and acute disseminated encephalomyelitis (ADEM). EAE is also the prototype for T-cell-mediated autoimmune disease in general.

EAE development was motivated by observations during the convalescence from viral diseases by Thomas M. Rivers, D. H. Sprunt and G. P. Berry in 1933. Their findings upon a transfer of inflamed patient tissue to primates was published in the Journal of Experimental Medicine. An acute monophasic illness, it has been suggested that EAE is far more similar to ADEM than to MS.