Codex Osuna is an Aztec codex on European paper, with indigenous pictorials and alphabetic Nahuatl text from 1565. It has seven parts, with most being economic in content, particularly tribute, with one part having historical content. It was named after the Spanish nobleman, Mariano Francisco de Borja José Justo Téllez-Girón y Beaufort-Spontin, twelfth Duke of Osuna, in whose library the codex was held until his death in 1882. It then became part of the collection of the Biblioteca Nacional in Madrid. It is part of a lawsuit by the indigenous of a Nahua community against Spaniards, and a fragment of a much larger Mexican text; the first numbered folio in the facsimile is 464.
The seven separate documents were created in early 1565 to present evidence against the government of Viceroy Luís de Velasco during the 1563-66 inquiry by Jerónimo de Valderrama. In this codex, indigenous leaders claim non-payment for various goods and for various services performed by their people, including building construction and domestic help. A modest black and white facsimile was published in Mexico by the Instituto Indigenista Interamericano in 1947, reproduced from the 1878 edition published in Madrid. The Mexican edition includes 158 pages of documentation in Spanish found in the Archivo General de la Nacion (Mexico) added by Luis Chávez Orozco.